Recombinant multi-species EED protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine EED protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein interacts with enhancer of zeste 2, the cytoplasmic tail of integrin beta7, immunodeficiency virus type 1 (HIV-1) MA protein, and histone deacetylase proteins. This protein mediates repression of gene activity through histone deacetylation, and may act as a specific regulator of integrin function. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
The Alternative Names of target: COGIS,EED,Eed,Embryonic ectoderm development protein,HEED,Polycomb protein EED,WAIT1,WD protein associating with integrin cytoplasmic tails 1 (WAIT-1),hEED,l(7)5Rn,l7Rn5,lusk
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T44916-Ag-1/ GM-Tg-hg-T44916-Ag-2 | Human EED protein | Human |
| GM-Tg-rg-T44916-Ag-1/ GM-Tg-rg-T44916-Ag-2 | Rat EED protein | Rat |
| GM-Tg-mg-T44916-Ag-1/ GM-Tg-mg-T44916-Ag-2 | Mouse EED protein | Mouse |
| GM-Tg-cynog-T44916-Ag-1/ GM-Tg-cynog-T44916-Ag-2 | Cynomolgus/Rhesus macaque EED protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T44916-Ag-1/ GM-Tg-felg-T44916-Ag-2 | Feline EED protein | Feline |
| GM-Tg-cang-T44916-Ag-1/ GM-Tg-cang-T44916-Ag-2 | Canine EED protein | Canine |
| GM-Tg-bovg-T44916-Ag-1/ GM-Tg-bovg-T44916-Ag-2 | Bovine EED protein | Bovine |
| GM-Tg-equg-T44916-Ag-1/ GM-Tg-equg-T44916-Ag-2 | Equine EED protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-T44916-Ag-1/ GM-Tg-hg-T44916-Ag-2;
GM-Tg-rg-T44916-Ag-1/ GM-Tg-rg-T44916-Ag-2;
GM-Tg-mg-T44916-Ag-1/ GM-Tg-mg-T44916-Ag-2; GM-Tg-cynog-T44916-Ag-1/ GM-Tg-cynog-T44916-Ag-2; GM-Tg-felg-T44916-Ag-1/ GM-Tg-felg-T44916-Ag-2; GM-Tg-cang-T44916-Ag-1/ GM-Tg-cang-T44916-Ag-2; GM-Tg-bovg-T44916-Ag-1/ GM-Tg-bovg-T44916-Ag-2; GM-Tg-equg-T44916-Ag-1/ GM-Tg-equg-T44916-Ag-2 |
| Products Name | EED protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | EED |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine EED protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.