Recombinant multi-species IL-22/IL22 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine IL-22/IL22 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene is a member of the IL10 family of cytokines that mediate cellular inflammatory responses. The encoded protein functions in antimicrobial defense at mucosal surfaces and in tissue repair. This protein also has pro-inflammatory properties and plays a role in in the pathogenesis of several intestinal diseases. The encoded protein is a crucial cytokine that regulates host immunity in infectious diseases, including COVID-19 (disease caused by SARS-CoV-2). [provided by RefSeq, Dec 2021]
The Alternative Names of target: Cytokine Zcyto18,IF2B1,IL-10-related T-cell-derived-inducible factor (IL-TIF),IL-21,IL-22,IL-D110,IL-TIF,IL22,ILTIF,If2b1,Il22,Interleukin-22,RGD1561292,TIFIL-23,TIFa,zcyto18

Target products collectionGo to IL-22/IL22 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T44682-Ag-1/ GM-Tg-hg-T44682-Ag-2 Human IL-22/IL22 protein Human
GM-Tg-rg-T44682-Ag-1/ GM-Tg-rg-T44682-Ag-2 Rat IL-22/IL22 protein Rat
GM-Tg-mg-T44682-Ag-1/ GM-Tg-mg-T44682-Ag-2 Mouse IL-22/IL22 protein Mouse
GM-Tg-cynog-T44682-Ag-1/ GM-Tg-cynog-T44682-Ag-2 Cynomolgus/Rhesus macaque IL-22/IL22 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T44682-Ag-1/ GM-Tg-felg-T44682-Ag-2 Feline IL-22/IL22 protein Feline
GM-Tg-cang-T44682-Ag-1/ GM-Tg-cang-T44682-Ag-2 Canine IL-22/IL22 protein Canine
GM-Tg-bovg-T44682-Ag-1/ GM-Tg-bovg-T44682-Ag-2 Bovine IL-22/IL22 protein Bovine
GM-Tg-equg-T44682-Ag-1/ GM-Tg-equg-T44682-Ag-2 Equine IL-22/IL22 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T44682-Ag-1/ GM-Tg-hg-T44682-Ag-2; GM-Tg-rg-T44682-Ag-1/ GM-Tg-rg-T44682-Ag-2;
GM-Tg-mg-T44682-Ag-1/ GM-Tg-mg-T44682-Ag-2; GM-Tg-cynog-T44682-Ag-1/ GM-Tg-cynog-T44682-Ag-2;
GM-Tg-felg-T44682-Ag-1/ GM-Tg-felg-T44682-Ag-2; GM-Tg-cang-T44682-Ag-1/ GM-Tg-cang-T44682-Ag-2;
GM-Tg-bovg-T44682-Ag-1/ GM-Tg-bovg-T44682-Ag-2; GM-Tg-equg-T44682-Ag-1/ GM-Tg-equg-T44682-Ag-2
Products Name IL-22/IL22 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name IL-22/IL22
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine IL-22/IL22 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.