Recombinant multi-species IL-17D/IL17D/IL27 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine IL-17D/IL17D/IL27 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is a cytokine that shares the sequence similarity with IL17. The treatment of endothelial cells with this cytokine has been shown to stimulate the production of other cytokines including IL6, IL8 and CSF2/ GM-CSF. The increased expression of IL8 induced by this cytokine was found to be NF-kappa B-dependent. [provided by RefSeq, Jul 2008]
The Alternative Names of target: IL-17D, IL17D, IL27,Interleukin-17D,IL-17D,Interleukin-27 (IL-27),IL-17D
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(antibodies,
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Product information
Catalog No. | Product Name | Species Reactivity |
---|---|---|
GM-Tg-hg-T41171-Ab-1/ GM-Tg-hg-T41171-Ab-2 | Human IL-17D/IL17D/IL27 protein | Human |
GM-Tg-rg-T41171-Ab-1/ GM-Tg-rg-T41171-Ab-2 | Rat IL-17D/IL17D/IL27 protein | Rat |
GM-Tg-mg-T41171-Ab-1/ GM-Tg-mg-T41171-Ab-2 | Mouse IL-17D/IL17D/IL27 protein | Mouse |
GM-Tg-cynog-T41171-Ab-1/ GM-Tg-cynog-T41171-Ab-2 | Cynomolgus/Rhesus macaque IL-17D/IL17D/IL27 monoclonal antibody | Cynomolgus/ Rhesus macaque |
GM-Tg-felg-T41171-Ab-1/ GM-Tg-felg-T41171-Ab-2 | Feline IL-17D/IL17D/IL27 protein | Feline |
GM-Tg-cang-T41171-Ab-1/ GM-Tg-cang-T41171-Ab-2 | Canine IL-17D/IL17D/IL27 protein | Canine |
GM-Tg-bovg-T41171-Ab-1/ GM-Tg-bovg-T41171-Ab-2 | Bovine IL-17D/IL17D/IL27 protein | Bovine |
GM-Tg-equg-T41171-Ab-1/ GM-Tg-equg-T41171-Ab-2 | Equine IL-17D/IL17D/IL27 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
Catalog No. |
GM-Tg-hg-T41171-Ab-1/ GM-Tg-hg-T41171-Ab-2;
GM-Tg-rg-T41171-Ab-1/ GM-Tg-rg-T41171-Ab-2;
GM-Tg-mg-T41171-Ab-1/ GM-Tg-mg-T41171-Ab-2; GM-Tg-cynog-T41171-Ab-1/ GM-Tg-cynog-T41171-Ab-2; GM-Tg-felg-T41171-Ab-1/ GM-Tg-felg-T41171-Ab-2; GM-Tg-cang-T41171-Ab-1/ GM-Tg-cang-T41171-Ab-2; GM-Tg-bovg-T41171-Ab-1/ GM-Tg-bovg-T41171-Ab-2; GM-Tg-equg-T41171-Ab-1/ GM-Tg-equg-T41171-Ab-2 |
Products Name | IL-17D/IL17D/IL27 protein |
Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
Target Name | IL-17D/IL17D/IL27 |
Protein Sub-location | Secreted Protein/Potential Cytokines |
Isotypes | Recombinant protein |
Expression platform | Mammalian cell |
Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
Tag | His |
Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine IL-17D/IL17D/IL27 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab
GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.