Recombinant multi-species PARP2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PARP2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes poly(ADP-ribosyl)transferase-like 2 protein, which contains a catalytic domain and is capable of catalyzing a poly(ADP-ribosyl)ation reaction. This protein has a catalytic domain which is homologous to that of poly (ADP-ribosyl) transferase, but lacks an N-terminal DNA binding domain which activates the C-terminal catalytic domain of poly (ADP-ribosyl) transferase. The basic residues within the N-terminal region of this protein may bear potential DNA-binding properties, and may be involved in the nuclear and/or nucleolar targeting of the protein. Two alternatively spliced transcript variants encoding distinct isoforms have been found. [provided by RefSeq, Jul 2008]
The Alternative Names of target: ADP-ribosyltransferase diphtheria toxin-like 2 (ARTD2),ADPRT-2,ADPRT2,ADPRTL2,ADPRTL3,ARTD2,Adprt2,Adprtl2,Aspartl2,DNA ADP-ribosyltransferase PARP2,NAD(+) ADP-ribosyltransferase 2 (ADPRT-2),PARP-2,PARP2,Parp2,Poly [ADP-ribose] polymerase 2,Poly[ADP-ribose] synthase 2 (pADPRT-2),Protein poly-ADP-ribosyltransferase PARP2,hPARP-2,mPARP-2,pADPRT-2
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T40812-Ag-1/ GM-Tg-hg-T40812-Ag-2 | Human PARP2 protein | Human |
| GM-Tg-rg-T40812-Ag-1/ GM-Tg-rg-T40812-Ag-2 | Rat PARP2 protein | Rat |
| GM-Tg-mg-T40812-Ag-1/ GM-Tg-mg-T40812-Ag-2 | Mouse PARP2 protein | Mouse |
| GM-Tg-cynog-T40812-Ag-1/ GM-Tg-cynog-T40812-Ag-2 | Cynomolgus/Rhesus macaque PARP2 protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T40812-Ag-1/ GM-Tg-felg-T40812-Ag-2 | Feline PARP2 protein | Feline |
| GM-Tg-cang-T40812-Ag-1/ GM-Tg-cang-T40812-Ag-2 | Canine PARP2 protein | Canine |
| GM-Tg-bovg-T40812-Ag-1/ GM-Tg-bovg-T40812-Ag-2 | Bovine PARP2 protein | Bovine |
| GM-Tg-equg-T40812-Ag-1/ GM-Tg-equg-T40812-Ag-2 | Equine PARP2 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-T40812-Ag-1/ GM-Tg-hg-T40812-Ag-2;
GM-Tg-rg-T40812-Ag-1/ GM-Tg-rg-T40812-Ag-2;
GM-Tg-mg-T40812-Ag-1/ GM-Tg-mg-T40812-Ag-2; GM-Tg-cynog-T40812-Ag-1/ GM-Tg-cynog-T40812-Ag-2; GM-Tg-felg-T40812-Ag-1/ GM-Tg-felg-T40812-Ag-2; GM-Tg-cang-T40812-Ag-1/ GM-Tg-cang-T40812-Ag-2; GM-Tg-bovg-T40812-Ag-1/ GM-Tg-bovg-T40812-Ag-2; GM-Tg-equg-T40812-Ag-1/ GM-Tg-equg-T40812-Ag-2 |
| Products Name | PARP2 protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | PARP2 |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PARP2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
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GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
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strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.