Recombinant multi-species Cathepsin H/CTSH protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine Cathepsin H/CTSH protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is a lysosomal cysteine proteinase important in the overall degradation of lysosomal proteins. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. The encoded protein, which belongs to the peptidase C1 protein family, can act both as an aminopeptidase and as an endopeptidase. Increased expression of this gene has been correlated with malignant progression of prostate tumors. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016]
The Alternative Names of target: Cathepsin H, CTSH,Pro-cathepsin H,ACC4,ACC5,CPSB,ACC-4,ACC-5

Target products collectionGo to Cathepsin H/CTSH products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T40103-Ab-1/ GM-Tg-hg-T40103-Ab-2 Human Cathepsin H/CTSH protein Human
GM-Tg-rg-T40103-Ab-1/ GM-Tg-rg-T40103-Ab-2 Rat Cathepsin H/CTSH protein Rat
GM-Tg-mg-T40103-Ab-1/ GM-Tg-mg-T40103-Ab-2 Mouse Cathepsin H/CTSH protein Mouse
GM-Tg-cynog-T40103-Ab-1/ GM-Tg-cynog-T40103-Ab-2 Cynomolgus/Rhesus macaque Cathepsin H/CTSH monoclonal antibody Cynomolgus/ Rhesus macaque
GM-Tg-felg-T40103-Ab-1/ GM-Tg-felg-T40103-Ab-2 Feline Cathepsin H/CTSH protein Feline
GM-Tg-cang-T40103-Ab-1/ GM-Tg-cang-T40103-Ab-2 Canine Cathepsin H/CTSH protein Canine
GM-Tg-bovg-T40103-Ab-1/ GM-Tg-bovg-T40103-Ab-2 Bovine Cathepsin H/CTSH protein Bovine
GM-Tg-equg-T40103-Ab-1/ GM-Tg-equg-T40103-Ab-2 Equine Cathepsin H/CTSH protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T40103-Ab-1/ GM-Tg-hg-T40103-Ab-2; GM-Tg-rg-T40103-Ab-1/ GM-Tg-rg-T40103-Ab-2;
GM-Tg-mg-T40103-Ab-1/ GM-Tg-mg-T40103-Ab-2; GM-Tg-cynog-T40103-Ab-1/ GM-Tg-cynog-T40103-Ab-2;
GM-Tg-felg-T40103-Ab-1/ GM-Tg-felg-T40103-Ab-2; GM-Tg-cang-T40103-Ab-1/ GM-Tg-cang-T40103-Ab-2;
GM-Tg-bovg-T40103-Ab-1/ GM-Tg-bovg-T40103-Ab-2; GM-Tg-equg-T40103-Ab-1/ GM-Tg-equg-T40103-Ab-2
Products Name Cathepsin H/CTSH protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name Cathepsin H/CTSH
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine Cathepsin H/CTSH protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

    GDU
    GDU

    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.