Recombinant multi-species CEL protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CEL protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is a glycoprotein secreted from the pancreas into the digestive tract and from the lactating mammary gland into human milk. The physiological role of this protein is in cholesterol and lipid-soluble vitamin ester hydrolysis and absorption. This encoded protein promotes large chylomicron production in the intestine. Also its presence in plasma suggests its interactions with cholesterol and oxidized lipoproteins to modulate the progression of atherosclerosis. In pancreatic tumoral cells, this encoded protein is thought to be sequestrated within the Golgi compartment and is probably not secreted. This gene contains a variable number of tandem repeat (VNTR) polymorphism in the coding region that may influence the function of the encoded protein. [provided by RefSeq, Jul 2008]
The Alternative Names of target: 1810036E18Rik,BAL,BSDL,BSSL,Bal,Bile salt-activated lipase,Bile salt-stimulated lipase (BSSL),Bssl,Bucelipase,CEL,CELL,CEase,Carboxyl ester lipase,Cel,Cholesterol esterase,FAP,FAPP,LIPA,MODY8,Pancreatic lysophospholipase,Sterol esterase

Target products collectionGo to CEL products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T39677-Ag-1/ GM-Tg-hg-T39677-Ag-2 Human CEL protein Human
GM-Tg-rg-T39677-Ag-1/ GM-Tg-rg-T39677-Ag-2 Rat CEL protein Rat
GM-Tg-mg-T39677-Ag-1/ GM-Tg-mg-T39677-Ag-2 Mouse CEL protein Mouse
GM-Tg-cynog-T39677-Ag-1/ GM-Tg-cynog-T39677-Ag-2 Cynomolgus/Rhesus macaque CEL protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T39677-Ag-1/ GM-Tg-felg-T39677-Ag-2 Feline CEL protein Feline
GM-Tg-cang-T39677-Ag-1/ GM-Tg-cang-T39677-Ag-2 Canine CEL protein Canine
GM-Tg-bovg-T39677-Ag-1/ GM-Tg-bovg-T39677-Ag-2 Bovine CEL protein Bovine
GM-Tg-equg-T39677-Ag-1/ GM-Tg-equg-T39677-Ag-2 Equine CEL protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T39677-Ag-1/ GM-Tg-hg-T39677-Ag-2; GM-Tg-rg-T39677-Ag-1/ GM-Tg-rg-T39677-Ag-2;
GM-Tg-mg-T39677-Ag-1/ GM-Tg-mg-T39677-Ag-2; GM-Tg-cynog-T39677-Ag-1/ GM-Tg-cynog-T39677-Ag-2;
GM-Tg-felg-T39677-Ag-1/ GM-Tg-felg-T39677-Ag-2; GM-Tg-cang-T39677-Ag-1/ GM-Tg-cang-T39677-Ag-2;
GM-Tg-bovg-T39677-Ag-1/ GM-Tg-bovg-T39677-Ag-2; GM-Tg-equg-T39677-Ag-1/ GM-Tg-equg-T39677-Ag-2
Products Name CEL protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name CEL
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CEL protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.