Recombinant multi-species CALM2/CALM protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CALM2/CALM protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene is a member of the calmodulin gene family. There are three distinct calmodulin genes dispersed throughout the genome that encode the identical protein, but differ at the nucleotide level. Calmodulin is a calcium binding protein that plays a role in signaling pathways, cell cycle progression and proliferation. Several infants with severe forms of long-QT syndrome (LQTS) who displayed life-threatening ventricular arrhythmias together with delayed neurodevelopment and epilepsy were found to have mutations in either this gene or another member of the calmodulin gene family (PMID:23388215). Mutations in this gene have also been identified in patients with less severe forms of LQTS (PMID:24917665), while mutations in another calmodulin gene family member have been associated with catecholaminergic polymorphic ventricular tachycardia (CPVT)(PMID:23040497), a rare disorder thought to be the cause of a significant fraction of sudden cardiac deaths in young individuals. Pseudogenes of this gene are found on chromosomes 10, 13, and 17. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2015]
The Alternative Names of target: 1500001E21Rik,CALM,CALM2,CALM3,CALML2,CAM1,CAM3,CAMC,CAMII,CAMIII,CaMII,Calm2,Calmodulin-2,Cam,Cam2,CamC,Camb,LQT15,PHKD,PHKD2,caM,calmodulin

Target products collectionGo to CALM2/CALM products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T39610-Ag-1/ GM-Tg-hg-T39610-Ag-2 Human CALM2/CALM protein Human
GM-Tg-rg-T39610-Ag-1/ GM-Tg-rg-T39610-Ag-2 Rat CALM2/CALM protein Rat
GM-Tg-mg-T39610-Ag-1/ GM-Tg-mg-T39610-Ag-2 Mouse CALM2/CALM protein Mouse
GM-Tg-cynog-T39610-Ag-1/ GM-Tg-cynog-T39610-Ag-2 Cynomolgus/Rhesus macaque CALM2/CALM protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T39610-Ag-1/ GM-Tg-felg-T39610-Ag-2 Feline CALM2/CALM protein Feline
GM-Tg-cang-T39610-Ag-1/ GM-Tg-cang-T39610-Ag-2 Canine CALM2/CALM protein Canine
GM-Tg-bovg-T39610-Ag-1/ GM-Tg-bovg-T39610-Ag-2 Bovine CALM2/CALM protein Bovine
GM-Tg-equg-T39610-Ag-1/ GM-Tg-equg-T39610-Ag-2 Equine CALM2/CALM protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T39610-Ag-1/ GM-Tg-hg-T39610-Ag-2; GM-Tg-rg-T39610-Ag-1/ GM-Tg-rg-T39610-Ag-2;
GM-Tg-mg-T39610-Ag-1/ GM-Tg-mg-T39610-Ag-2; GM-Tg-cynog-T39610-Ag-1/ GM-Tg-cynog-T39610-Ag-2;
GM-Tg-felg-T39610-Ag-1/ GM-Tg-felg-T39610-Ag-2; GM-Tg-cang-T39610-Ag-1/ GM-Tg-cang-T39610-Ag-2;
GM-Tg-bovg-T39610-Ag-1/ GM-Tg-bovg-T39610-Ag-2; GM-Tg-equg-T39610-Ag-1/ GM-Tg-equg-T39610-Ag-2
Products Name CALM2/CALM protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name CALM2/CALM
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CALM2/CALM protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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