Recombinant multi-species TNKS2/TNKS-2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TNKS2/TNKS-2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Enables NAD+ ADP-ribosyltransferase activity; enzyme binding activity; and protein ADP-ribosylase activity. Involved in several processes, including protein ADP-ribosylation; protein localization to chromosome, telomeric region; and regulation of telomere maintenance. Located in nuclear envelope; pericentriolar material; and perinuclear region of cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]
The Alternative Names of target: 5430432P15Rik,ADP-ribosyltransferase diphtheria toxin-like 6 (ARTD6),ARTD6,PARP-5b,PARP-5c,PARP5B,PARP5C,Parp5b,Poly [ADP-ribose] polymerase 5B,Poly [ADP-ribose] polymerase tankyrase-2,Protein poly-ADP-ribosyltransferase tankyrase-2,TANK2,TNKL,TNKS-2,TNKS2,TRF1-interacting ankyrin-related ADP-ribose polymerase 2,Tank2,Tankyrase II,Tankyrase-2 (TANK2),Tankyrase-like protein,Tankyrase-related protein,Tnks2,pART6

Target products collectionGo to TNKS2/TNKS-2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T38087-Ag-1/ GM-Tg-hg-T38087-Ag-2 Human TNKS2/TNKS-2 protein Human
GM-Tg-rg-T38087-Ag-1/ GM-Tg-rg-T38087-Ag-2 Rat TNKS2/TNKS-2 protein Rat
GM-Tg-mg-T38087-Ag-1/ GM-Tg-mg-T38087-Ag-2 Mouse TNKS2/TNKS-2 protein Mouse
GM-Tg-cynog-T38087-Ag-1/ GM-Tg-cynog-T38087-Ag-2 Cynomolgus/Rhesus macaque TNKS2/TNKS-2 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T38087-Ag-1/ GM-Tg-felg-T38087-Ag-2 Feline TNKS2/TNKS-2 protein Feline
GM-Tg-cang-T38087-Ag-1/ GM-Tg-cang-T38087-Ag-2 Canine TNKS2/TNKS-2 protein Canine
GM-Tg-bovg-T38087-Ag-1/ GM-Tg-bovg-T38087-Ag-2 Bovine TNKS2/TNKS-2 protein Bovine
GM-Tg-equg-T38087-Ag-1/ GM-Tg-equg-T38087-Ag-2 Equine TNKS2/TNKS-2 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T38087-Ag-1/ GM-Tg-hg-T38087-Ag-2; GM-Tg-rg-T38087-Ag-1/ GM-Tg-rg-T38087-Ag-2;
GM-Tg-mg-T38087-Ag-1/ GM-Tg-mg-T38087-Ag-2; GM-Tg-cynog-T38087-Ag-1/ GM-Tg-cynog-T38087-Ag-2;
GM-Tg-felg-T38087-Ag-1/ GM-Tg-felg-T38087-Ag-2; GM-Tg-cang-T38087-Ag-1/ GM-Tg-cang-T38087-Ag-2;
GM-Tg-bovg-T38087-Ag-1/ GM-Tg-bovg-T38087-Ag-2; GM-Tg-equg-T38087-Ag-1/ GM-Tg-equg-T38087-Ag-2
Products Name TNKS2/TNKS-2 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name TNKS2/TNKS-2
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TNKS2/TNKS-2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.