Recombinant multi-species CA7/CA-VII protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CA7/CA-VII protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Carbonic anhydrases are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. The cytosolic protein encoded by this gene is predominantly expressed in the brain and contributes to bicarbonate driven GABAergic neuron excitation. Alternative splicing in the coding region results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2018]
The Alternative Names of target: CA-VII,CA7,CAVII,Ca7,Car7,Carbonate dehydratase VII,Carbonic anhydrase 7,Carbonic anhydrase VII (CA-VII)

Target products collectionGo to CA7/CA-VII products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T37541-Ag-1/ GM-Tg-hg-T37541-Ag-2 Human CA7/CA-VII protein Human
GM-Tg-rg-T37541-Ag-1/ GM-Tg-rg-T37541-Ag-2 Rat CA7/CA-VII protein Rat
GM-Tg-mg-T37541-Ag-1/ GM-Tg-mg-T37541-Ag-2 Mouse CA7/CA-VII protein Mouse
GM-Tg-cynog-T37541-Ag-1/ GM-Tg-cynog-T37541-Ag-2 Cynomolgus/Rhesus macaque CA7/CA-VII protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T37541-Ag-1/ GM-Tg-felg-T37541-Ag-2 Feline CA7/CA-VII protein Feline
GM-Tg-cang-T37541-Ag-1/ GM-Tg-cang-T37541-Ag-2 Canine CA7/CA-VII protein Canine
GM-Tg-bovg-T37541-Ag-1/ GM-Tg-bovg-T37541-Ag-2 Bovine CA7/CA-VII protein Bovine
GM-Tg-equg-T37541-Ag-1/ GM-Tg-equg-T37541-Ag-2 Equine CA7/CA-VII protein Equine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T37541-Ag-1/ GM-Tg-hg-T37541-Ag-2; GM-Tg-rg-T37541-Ag-1/ GM-Tg-rg-T37541-Ag-2;
GM-Tg-mg-T37541-Ag-1/ GM-Tg-mg-T37541-Ag-2; GM-Tg-cynog-T37541-Ag-1/ GM-Tg-cynog-T37541-Ag-2;
GM-Tg-felg-T37541-Ag-1/ GM-Tg-felg-T37541-Ag-2; GM-Tg-cang-T37541-Ag-1/ GM-Tg-cang-T37541-Ag-2;
GM-Tg-bovg-T37541-Ag-1/ GM-Tg-bovg-T37541-Ag-2; GM-Tg-equg-T37541-Ag-1/ GM-Tg-equg-T37541-Ag-2
Products Name CA7/CA-VII protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name CA7/CA-VII
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CA7/CA-VII protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.