Recombinant multi-species CA7/CA-VII protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CA7/CA-VII protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Carbonic anhydrases are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. The cytosolic protein encoded by this gene is predominantly expressed in the brain and contributes to bicarbonate driven GABAergic neuron excitation. Alternative splicing in the coding region results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2018]
The Alternative Names of target: CA-VII,CA7,CAVII,Ca7,Car7,Carbonate dehydratase VII,Carbonic anhydrase 7,Carbonic anhydrase VII (CA-VII)
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T37541-Ag-1/ GM-Tg-hg-T37541-Ag-2 | Human CA7/CA-VII protein | Human |
| GM-Tg-rg-T37541-Ag-1/ GM-Tg-rg-T37541-Ag-2 | Rat CA7/CA-VII protein | Rat |
| GM-Tg-mg-T37541-Ag-1/ GM-Tg-mg-T37541-Ag-2 | Mouse CA7/CA-VII protein | Mouse |
| GM-Tg-cynog-T37541-Ag-1/ GM-Tg-cynog-T37541-Ag-2 | Cynomolgus/Rhesus macaque CA7/CA-VII protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T37541-Ag-1/ GM-Tg-felg-T37541-Ag-2 | Feline CA7/CA-VII protein | Feline |
| GM-Tg-cang-T37541-Ag-1/ GM-Tg-cang-T37541-Ag-2 | Canine CA7/CA-VII protein | Canine |
| GM-Tg-bovg-T37541-Ag-1/ GM-Tg-bovg-T37541-Ag-2 | Bovine CA7/CA-VII protein | Bovine |
| GM-Tg-equg-T37541-Ag-1/ GM-Tg-equg-T37541-Ag-2 | Equine CA7/CA-VII protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-T37541-Ag-1/ GM-Tg-hg-T37541-Ag-2;
GM-Tg-rg-T37541-Ag-1/ GM-Tg-rg-T37541-Ag-2;
GM-Tg-mg-T37541-Ag-1/ GM-Tg-mg-T37541-Ag-2; GM-Tg-cynog-T37541-Ag-1/ GM-Tg-cynog-T37541-Ag-2; GM-Tg-felg-T37541-Ag-1/ GM-Tg-felg-T37541-Ag-2; GM-Tg-cang-T37541-Ag-1/ GM-Tg-cang-T37541-Ag-2; GM-Tg-bovg-T37541-Ag-1/ GM-Tg-bovg-T37541-Ag-2; GM-Tg-equg-T37541-Ag-1/ GM-Tg-equg-T37541-Ag-2 |
| Products Name | CA7/CA-VII protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | CA7/CA-VII |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CA7/CA-VII protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.