Recombinant multi-species PCSK1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PCSK1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an initial autocatalytic processing event in the ER to generate a heterodimer which exits the ER and sorts to subcellular compartments where a second autocatalytic even takes place and the catalytic activity is acquired. The protease is packaged into and activated in dense core secretory granules and expressed in the neuroendocrine system and brain. This gene encodes one of the seven basic amino acid-specific members which cleave their substrates at single or paired basic residues. It functions in the proteolytic activation of polypeptide hormones and neuropeptides precursors. Mutations in this gene have been associated with susceptibility to obesity and proprotein convertase 1/3 deficiency. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene [provided by RefSeq, Jan 2014]
The Alternative Names of target: BDP,BMIQ12,NEC 1,NEC1,Nec-1,Nec1,Neuroendocrine convertase 1,PC1,PC1/3,PC3,PCSK1,Pcsk1,Phpp-1,Prohormone convertase 1,Proprotein convertase 1 (PC1),SPC3

Target products collectionGo to PCSK1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T36445-Ag-1/ GM-Tg-hg-T36445-Ag-2 Human PCSK1 protein Human
GM-Tg-rg-T36445-Ag-1/ GM-Tg-rg-T36445-Ag-2 Rat PCSK1 protein Rat
GM-Tg-mg-T36445-Ag-1/ GM-Tg-mg-T36445-Ag-2 Mouse PCSK1 protein Mouse
GM-Tg-cynog-T36445-Ag-1/ GM-Tg-cynog-T36445-Ag-2 Cynomolgus/Rhesus macaque PCSK1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T36445-Ag-1/ GM-Tg-felg-T36445-Ag-2 Feline PCSK1 protein Feline
GM-Tg-cang-T36445-Ag-1/ GM-Tg-cang-T36445-Ag-2 Canine PCSK1 protein Canine
GM-Tg-bovg-T36445-Ag-1/ GM-Tg-bovg-T36445-Ag-2 Bovine PCSK1 protein Bovine
GM-Tg-equg-T36445-Ag-1/ GM-Tg-equg-T36445-Ag-2 Equine PCSK1 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T36445-Ag-1/ GM-Tg-hg-T36445-Ag-2; GM-Tg-rg-T36445-Ag-1/ GM-Tg-rg-T36445-Ag-2;
GM-Tg-mg-T36445-Ag-1/ GM-Tg-mg-T36445-Ag-2; GM-Tg-cynog-T36445-Ag-1/ GM-Tg-cynog-T36445-Ag-2;
GM-Tg-felg-T36445-Ag-1/ GM-Tg-felg-T36445-Ag-2; GM-Tg-cang-T36445-Ag-1/ GM-Tg-cang-T36445-Ag-2;
GM-Tg-bovg-T36445-Ag-1/ GM-Tg-bovg-T36445-Ag-2; GM-Tg-equg-T36445-Ag-1/ GM-Tg-equg-T36445-Ag-2
Products Name PCSK1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name PCSK1
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PCSK1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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