Recombinant multi-species IL-7/IL7 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine IL-7/IL7 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is a cytokine important for B and T cell development. This cytokine and the hepatocyte growth factor (HGF) form a heterodimer that functions as a pre-pro-B cell growth-stimulating factor. IL7 is found to be a cofactor for V(D)J rearrangement of the T cell receptor beta (TCRB) during early T cell development. This cytokine can be produced locally by intestinal epithelial and epithelial goblet cells, and may serve as a regulatory factor for intestinal mucosal lymphocytes. IL7 plays an essential role in lymphoid cell survival, and in the maintenance of naive and memory T cells. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their presence in normal tissues has not been confirmed. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection can be a potent inducer of proinflammatory cytokines and chemokines which may defend against the infection, but may also mediate destructive lung injury. Elevated serum IL7 levels, together with several other circulating cytokines and chemokines, has been found to be associated with the severity of Coronavirus Disease 19 (COVID-19). [provided by RefSeq, Jul 2020]
The Alternative Names of target: A630026I06Rik,IL-7,IL7,IMD130,Il-7,Il7,Interleukin-7,hlb368

Target products collectionGo to IL-7/IL7 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T35232-Ag-1/ GM-Tg-hg-T35232-Ag-2 Human IL-7/IL7 protein Human
GM-Tg-rg-T35232-Ag-1/ GM-Tg-rg-T35232-Ag-2 Rat IL-7/IL7 protein Rat
GM-Tg-mg-T35232-Ag-1/ GM-Tg-mg-T35232-Ag-2 Mouse IL-7/IL7 protein Mouse
GM-Tg-cynog-T35232-Ag-1/ GM-Tg-cynog-T35232-Ag-2 Cynomolgus/Rhesus macaque IL-7/IL7 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T35232-Ag-1/ GM-Tg-felg-T35232-Ag-2 Feline IL-7/IL7 protein Feline
GM-Tg-cang-T35232-Ag-1/ GM-Tg-cang-T35232-Ag-2 Canine IL-7/IL7 protein Canine
GM-Tg-bovg-T35232-Ag-1/ GM-Tg-bovg-T35232-Ag-2 Bovine IL-7/IL7 protein Bovine
GM-Tg-equg-T35232-Ag-1/ GM-Tg-equg-T35232-Ag-2 Equine IL-7/IL7 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T35232-Ag-1/ GM-Tg-hg-T35232-Ag-2; GM-Tg-rg-T35232-Ag-1/ GM-Tg-rg-T35232-Ag-2;
GM-Tg-mg-T35232-Ag-1/ GM-Tg-mg-T35232-Ag-2; GM-Tg-cynog-T35232-Ag-1/ GM-Tg-cynog-T35232-Ag-2;
GM-Tg-felg-T35232-Ag-1/ GM-Tg-felg-T35232-Ag-2; GM-Tg-cang-T35232-Ag-1/ GM-Tg-cang-T35232-Ag-2;
GM-Tg-bovg-T35232-Ag-1/ GM-Tg-bovg-T35232-Ag-2; GM-Tg-equg-T35232-Ag-1/ GM-Tg-equg-T35232-Ag-2
Products Name IL-7/IL7 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name IL-7/IL7
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine IL-7/IL7 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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