Recombinant multi-species HSPB8 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine HSPB8 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease. [provided by RefSeq, Jul 2008]
The Alternative Names of target: Alpha-crystallin C chain,CMT2L,Cryac,D5Ucla4,DHMN2,E2-induced gene 1 protein,E2IG1,H11,H11K,HMN2,HMN2A,HMND2,HSP20-like,HSP22,HSPB8,HSPB8-N1,HSPB8-N2,Heat shock protein beta-8,Heat shock protein family B member 8,Hsp22,HspB8,Hspb8,Protein kinase H11,Small stress protein-like protein HSP22

Target products collectionGo to HSPB8 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T35161-Ag-1/ GM-Tg-hg-T35161-Ag-2 Human HSPB8 protein Human
GM-Tg-rg-T35161-Ag-1/ GM-Tg-rg-T35161-Ag-2 Rat HSPB8 protein Rat
GM-Tg-mg-T35161-Ag-1/ GM-Tg-mg-T35161-Ag-2 Mouse HSPB8 protein Mouse
GM-Tg-cynog-T35161-Ag-1/ GM-Tg-cynog-T35161-Ag-2 Cynomolgus/Rhesus macaque HSPB8 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T35161-Ag-1/ GM-Tg-felg-T35161-Ag-2 Feline HSPB8 protein Feline
GM-Tg-cang-T35161-Ag-1/ GM-Tg-cang-T35161-Ag-2 Canine HSPB8 protein Canine
GM-Tg-bovg-T35161-Ag-1/ GM-Tg-bovg-T35161-Ag-2 Bovine HSPB8 protein Bovine
GM-Tg-equg-T35161-Ag-1/ GM-Tg-equg-T35161-Ag-2 Equine HSPB8 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T35161-Ag-1/ GM-Tg-hg-T35161-Ag-2; GM-Tg-rg-T35161-Ag-1/ GM-Tg-rg-T35161-Ag-2;
GM-Tg-mg-T35161-Ag-1/ GM-Tg-mg-T35161-Ag-2; GM-Tg-cynog-T35161-Ag-1/ GM-Tg-cynog-T35161-Ag-2;
GM-Tg-felg-T35161-Ag-1/ GM-Tg-felg-T35161-Ag-2; GM-Tg-cang-T35161-Ag-1/ GM-Tg-cang-T35161-Ag-2;
GM-Tg-bovg-T35161-Ag-1/ GM-Tg-bovg-T35161-Ag-2; GM-Tg-equg-T35161-Ag-1/ GM-Tg-equg-T35161-Ag-2
Products Name HSPB8 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name HSPB8
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine HSPB8 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.