Recombinant multi-species APOC3/ApoCIII protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine APOC3/ApoCIII protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a protein component of triglyceride (TG)-rich lipoproteins (TRLs) including very low density lipoproteins (VLDL), high density lipoproteins (HDL) and chylomicrons. The encoded protein plays a role in role in the metabolism of these TRLs through multiple modes. This protein has been shown to promote the secretion of VLDL1, inhibit lipoprotein lipase enzyme activity, and delay catabolism of TRL remnants. Mutations in this gene are associated with low plasma triglyceride levels and reduced risk of ischemic cardiovascular disease, and hyperalphalipoproteinemia, which is characterized by elevated levels of high density lipoprotein (HDL) and HDL cholesterol in human patients. This gene and other related genes comprise an apolipoprotein gene cluster on chromosome 11. [provided by RefSeq, Sep 2017]
The Alternative Names of target: APOC3,APOCIII,Apo-C3,Apo-CIII,ApoC-3,ApoC-III,ApoCIII,Apoc3,Apolipoprotein C-III,Apolipoprotein C3,apo-CIII,apoC-III
Go
to APOC3/ApoCIII products collection
>>
(antibodies,
antigen, VLP, mRNA, ORF viral vector, etc)
Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T31518-Ag-1/ GM-Tg-hg-T31518-Ag-2 | Human APOC3/ApoCIII protein | Human |
| GM-Tg-rg-T31518-Ag-1/ GM-Tg-rg-T31518-Ag-2 | Rat APOC3/ApoCIII protein | Rat |
| GM-Tg-mg-T31518-Ag-1/ GM-Tg-mg-T31518-Ag-2 | Mouse APOC3/ApoCIII protein | Mouse |
| GM-Tg-cynog-T31518-Ag-1/ GM-Tg-cynog-T31518-Ag-2 | Cynomolgus/Rhesus macaque APOC3/ApoCIII protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T31518-Ag-1/ GM-Tg-felg-T31518-Ag-2 | Feline APOC3/ApoCIII protein | Feline |
| GM-Tg-cang-T31518-Ag-1/ GM-Tg-cang-T31518-Ag-2 | Canine APOC3/ApoCIII protein | Canine |
| GM-Tg-bovg-T31518-Ag-1/ GM-Tg-bovg-T31518-Ag-2 | Bovine APOC3/ApoCIII protein | Bovine |
| GM-Tg-equg-T31518-Ag-1/ GM-Tg-equg-T31518-Ag-2 | Equine APOC3/ApoCIII protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-T31518-Ag-1/ GM-Tg-hg-T31518-Ag-2;
GM-Tg-rg-T31518-Ag-1/ GM-Tg-rg-T31518-Ag-2;
GM-Tg-mg-T31518-Ag-1/ GM-Tg-mg-T31518-Ag-2; GM-Tg-cynog-T31518-Ag-1/ GM-Tg-cynog-T31518-Ag-2; GM-Tg-felg-T31518-Ag-1/ GM-Tg-felg-T31518-Ag-2; GM-Tg-cang-T31518-Ag-1/ GM-Tg-cang-T31518-Ag-2; GM-Tg-bovg-T31518-Ag-1/ GM-Tg-bovg-T31518-Ag-2; GM-Tg-equg-T31518-Ag-1/ GM-Tg-equg-T31518-Ag-2 |
| Products Name | APOC3/ApoCIII protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | APOC3/ApoCIII |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine APOC3/ApoCIII protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.