Recombinant multi-species BSAP/PAX5 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine BSAP/PAX5 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the paired box (PAX) family of transcription factors. The central feature of this gene family is a novel, highly conserved DNA-binding motif, known as the paired box. Paired box transcription factors are important regulators in early development, and alterations in the expression of their genes are thought to contribute to neoplastic transformation. This gene encodes the B-cell lineage specific activator protein that is expressed at early, but not late stages of B-cell differentiation. Its expression has also been detected in developing CNS and testis and so the encoded protein may also play a role in neural development and spermatogenesis. This gene is located at 9p13, which is involved in t(9;14)(p13;q32) translocations recurring in small lymphocytic lymphomas of the plasmacytoid subtype, and in derived large-cell lymphomas. This translocation brings the potent E-mu enhancer of the IgH gene into close proximity of the PAX5 promoter, suggesting that the deregulation of transcription of this gene contributes to the pathogenesis of these lymphomas. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013]
The Alternative Names of target: ALL3,B-cell-specific transcription factor (BSAP),BSAP,EBB-1,KLP,PAX-5,PAX5,Paired box protein Pax-5,Pax-5,Pax5,RGD1565236

Target products collectionGo to BSAP/PAX5 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T29818-Ag-1/ GM-Tg-hg-T29818-Ag-2 Human BSAP/PAX5 protein Human
GM-Tg-rg-T29818-Ag-1/ GM-Tg-rg-T29818-Ag-2 Rat BSAP/PAX5 protein Rat
GM-Tg-mg-T29818-Ag-1/ GM-Tg-mg-T29818-Ag-2 Mouse BSAP/PAX5 protein Mouse
GM-Tg-cynog-T29818-Ag-1/ GM-Tg-cynog-T29818-Ag-2 Cynomolgus/Rhesus macaque BSAP/PAX5 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T29818-Ag-1/ GM-Tg-felg-T29818-Ag-2 Feline BSAP/PAX5 protein Feline
GM-Tg-cang-T29818-Ag-1/ GM-Tg-cang-T29818-Ag-2 Canine BSAP/PAX5 protein Canine
GM-Tg-bovg-T29818-Ag-1/ GM-Tg-bovg-T29818-Ag-2 Bovine BSAP/PAX5 protein Bovine
GM-Tg-equg-T29818-Ag-1/ GM-Tg-equg-T29818-Ag-2 Equine BSAP/PAX5 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T29818-Ag-1/ GM-Tg-hg-T29818-Ag-2; GM-Tg-rg-T29818-Ag-1/ GM-Tg-rg-T29818-Ag-2;
GM-Tg-mg-T29818-Ag-1/ GM-Tg-mg-T29818-Ag-2; GM-Tg-cynog-T29818-Ag-1/ GM-Tg-cynog-T29818-Ag-2;
GM-Tg-felg-T29818-Ag-1/ GM-Tg-felg-T29818-Ag-2; GM-Tg-cang-T29818-Ag-1/ GM-Tg-cang-T29818-Ag-2;
GM-Tg-bovg-T29818-Ag-1/ GM-Tg-bovg-T29818-Ag-2; GM-Tg-equg-T29818-Ag-1/ GM-Tg-equg-T29818-Ag-2
Products Name BSAP/PAX5 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name BSAP/PAX5
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine BSAP/PAX5 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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