Recombinant multi-species FGF-4/FGF4 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine FGF-4/FGF4 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was identified by its oncogenic transforming activity. This gene and FGF3, another oncogenic growth factor, are located closely on chromosome 11. Co-amplification of both genes was found in various kinds of human tumors. Studies on the mouse homolog suggested a function in bone morphogenesis and limb development through the sonic hedgehog (SHH) signaling pathway. [provided by RefSeq, Jul 2008]
The Alternative Names of target: FGF-4,FGF4,Fgf-4,Fgf4,Fgf7a,Fgfk,Fibroblast growth factor 4,HBGF-4,HST,HST-1,HSTF-1,HSTF-1),HSTF1,Heparin secretory-transforming protein 1 (HST,Heparin-binding growth factor 4 (HBGF-4),Hst,Hst1,Hstf-1,K-FGF,KFGF,KS3,Transforming protein KS3,hst,hst-1,kFGF
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T28076-Ag-1/ GM-Tg-hg-T28076-Ag-2 | Human FGF-4/FGF4 protein | Human |
| GM-Tg-rg-T28076-Ag-1/ GM-Tg-rg-T28076-Ag-2 | Rat FGF-4/FGF4 protein | Rat |
| GM-Tg-mg-T28076-Ag-1/ GM-Tg-mg-T28076-Ag-2 | Mouse FGF-4/FGF4 protein | Mouse |
| GM-Tg-cynog-T28076-Ag-1/ GM-Tg-cynog-T28076-Ag-2 | Cynomolgus/Rhesus macaque FGF-4/FGF4 protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T28076-Ag-1/ GM-Tg-felg-T28076-Ag-2 | Feline FGF-4/FGF4 protein | Feline |
| GM-Tg-cang-T28076-Ag-1/ GM-Tg-cang-T28076-Ag-2 | Canine FGF-4/FGF4 protein | Canine |
| GM-Tg-bovg-T28076-Ag-1/ GM-Tg-bovg-T28076-Ag-2 | Bovine FGF-4/FGF4 protein | Bovine |
| GM-Tg-equg-T28076-Ag-1/ GM-Tg-equg-T28076-Ag-2 | Equine FGF-4/FGF4 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-T28076-Ag-1/ GM-Tg-hg-T28076-Ag-2;
GM-Tg-rg-T28076-Ag-1/ GM-Tg-rg-T28076-Ag-2;
GM-Tg-mg-T28076-Ag-1/ GM-Tg-mg-T28076-Ag-2; GM-Tg-cynog-T28076-Ag-1/ GM-Tg-cynog-T28076-Ag-2; GM-Tg-felg-T28076-Ag-1/ GM-Tg-felg-T28076-Ag-2; GM-Tg-cang-T28076-Ag-1/ GM-Tg-cang-T28076-Ag-2; GM-Tg-bovg-T28076-Ag-1/ GM-Tg-bovg-T28076-Ag-2; GM-Tg-equg-T28076-Ag-1/ GM-Tg-equg-T28076-Ag-2 |
| Products Name | FGF-4/FGF4 protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | FGF-4/FGF4 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine FGF-4/FGF4 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.