Recombinant multi-species SPTBN1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine SPTBN1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. It is composed of two antiparallel dimers of alpha- and beta- subunits. This gene is one member of a family of beta-spectrin genes. The encoded protein contains an N-terminal actin-binding domain, and 17 spectrin repeats which are involved in dimer formation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
The Alternative Names of target: SPTBN1,Spectrin beta chain, non-erythrocytic 1,Beta-II spectrin, Fodrin beta chain, Spectrin, non-erythroid beta chain 1,ELF,SPTB2,DDISBA,HEL102,betaSpII

Target products collectionGo to SPTBN1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T27826-Ab-1/ GM-Tg-hg-T27826-Ab-2 Human SPTBN1 protein Human
GM-Tg-rg-T27826-Ab-1/ GM-Tg-rg-T27826-Ab-2 Rat SPTBN1 protein Rat
GM-Tg-mg-T27826-Ab-1/ GM-Tg-mg-T27826-Ab-2 Mouse SPTBN1 protein Mouse
GM-Tg-cynog-T27826-Ab-1/ GM-Tg-cynog-T27826-Ab-2 Cynomolgus/Rhesus macaque SPTBN1 monoclonal antibody Cynomolgus/ Rhesus macaque
GM-Tg-felg-T27826-Ab-1/ GM-Tg-felg-T27826-Ab-2 Feline SPTBN1 protein Feline
GM-Tg-cang-T27826-Ab-1/ GM-Tg-cang-T27826-Ab-2 Canine SPTBN1 protein Canine
GM-Tg-bovg-T27826-Ab-1/ GM-Tg-bovg-T27826-Ab-2 Bovine SPTBN1 protein Bovine
GM-Tg-equg-T27826-Ab-1/ GM-Tg-equg-T27826-Ab-2 Equine SPTBN1 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T27826-Ab-1/ GM-Tg-hg-T27826-Ab-2; GM-Tg-rg-T27826-Ab-1/ GM-Tg-rg-T27826-Ab-2;
GM-Tg-mg-T27826-Ab-1/ GM-Tg-mg-T27826-Ab-2; GM-Tg-cynog-T27826-Ab-1/ GM-Tg-cynog-T27826-Ab-2;
GM-Tg-felg-T27826-Ab-1/ GM-Tg-felg-T27826-Ab-2; GM-Tg-cang-T27826-Ab-1/ GM-Tg-cang-T27826-Ab-2;
GM-Tg-bovg-T27826-Ab-1/ GM-Tg-bovg-T27826-Ab-2; GM-Tg-equg-T27826-Ab-1/ GM-Tg-equg-T27826-Ab-2
Products Name SPTBN1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name SPTBN1
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine SPTBN1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.