Recombinant multi-species Cyclophilin B/PPIB protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine Cyclophilin B/PPIB protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is a cyclosporine-binding protein and is mainly located within the endoplasmic reticulum. It is associated with the secretory pathway and released in biological fluids. This protein can bind to cells derived from T- and B-lymphocytes, and may regulate cyclosporine A-mediated immunosuppression. Variants have been identified in this protein that give rise to recessive forms of osteogenesis imperfecta. [provided by RefSeq, Oct 2009]
The Alternative Names of target: Cyclophilin B, PPIB,Peptidyl-prolyl cis-trans isomerase B,PPIase B,CYP-S1, Cyclophilin B, Rotamase B, S-cyclophilin (SCYLP),OI9,CYPB,SCYLP,CYP-S1,HEL-S-39

Target products collectionGo to Cyclophilin B/PPIB products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T25847-Ab-1/ GM-Tg-hg-T25847-Ab-2 Human Cyclophilin B/PPIB protein Human
GM-Tg-rg-T25847-Ab-1/ GM-Tg-rg-T25847-Ab-2 Rat Cyclophilin B/PPIB protein Rat
GM-Tg-mg-T25847-Ab-1/ GM-Tg-mg-T25847-Ab-2 Mouse Cyclophilin B/PPIB protein Mouse
GM-Tg-cynog-T25847-Ab-1/ GM-Tg-cynog-T25847-Ab-2 Cynomolgus/Rhesus macaque Cyclophilin B/PPIB monoclonal antibody Cynomolgus/ Rhesus macaque
GM-Tg-felg-T25847-Ab-1/ GM-Tg-felg-T25847-Ab-2 Feline Cyclophilin B/PPIB protein Feline
GM-Tg-cang-T25847-Ab-1/ GM-Tg-cang-T25847-Ab-2 Canine Cyclophilin B/PPIB protein Canine
GM-Tg-bovg-T25847-Ab-1/ GM-Tg-bovg-T25847-Ab-2 Bovine Cyclophilin B/PPIB protein Bovine
GM-Tg-equg-T25847-Ab-1/ GM-Tg-equg-T25847-Ab-2 Equine Cyclophilin B/PPIB protein Equine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T25847-Ab-1/ GM-Tg-hg-T25847-Ab-2; GM-Tg-rg-T25847-Ab-1/ GM-Tg-rg-T25847-Ab-2;
GM-Tg-mg-T25847-Ab-1/ GM-Tg-mg-T25847-Ab-2; GM-Tg-cynog-T25847-Ab-1/ GM-Tg-cynog-T25847-Ab-2;
GM-Tg-felg-T25847-Ab-1/ GM-Tg-felg-T25847-Ab-2; GM-Tg-cang-T25847-Ab-1/ GM-Tg-cang-T25847-Ab-2;
GM-Tg-bovg-T25847-Ab-1/ GM-Tg-bovg-T25847-Ab-2; GM-Tg-equg-T25847-Ab-1/ GM-Tg-equg-T25847-Ab-2
Products Name Cyclophilin B/PPIB protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name Cyclophilin B/PPIB
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine Cyclophilin B/PPIB protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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