Recombinant multi-species Cyclophilin B/PPIB protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine Cyclophilin B/PPIB protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is a cyclosporine-binding protein and is mainly located within the endoplasmic reticulum. It is associated with the secretory pathway and released in biological fluids. This protein can bind to cells derived from T- and B-lymphocytes, and may regulate cyclosporine A-mediated immunosuppression. Variants have been identified in this protein that give rise to recessive forms of osteogenesis imperfecta. [provided by RefSeq, Oct 2009]
The Alternative Names of target: Cyclophilin B, PPIB,Peptidyl-prolyl cis-trans isomerase B,PPIase B,CYP-S1, Cyclophilin B, Rotamase B, S-cyclophilin (SCYLP),OI9,CYPB,SCYLP,CYP-S1,HEL-S-39
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Product information
Catalog No. | Product Name | Species Reactivity |
---|---|---|
GM-Tg-hg-T25847-Ab-1/ GM-Tg-hg-T25847-Ab-2 | Human Cyclophilin B/PPIB protein | Human |
GM-Tg-rg-T25847-Ab-1/ GM-Tg-rg-T25847-Ab-2 | Rat Cyclophilin B/PPIB protein | Rat |
GM-Tg-mg-T25847-Ab-1/ GM-Tg-mg-T25847-Ab-2 | Mouse Cyclophilin B/PPIB protein | Mouse |
GM-Tg-cynog-T25847-Ab-1/ GM-Tg-cynog-T25847-Ab-2 | Cynomolgus/Rhesus macaque Cyclophilin B/PPIB monoclonal antibody | Cynomolgus/ Rhesus macaque |
GM-Tg-felg-T25847-Ab-1/ GM-Tg-felg-T25847-Ab-2 | Feline Cyclophilin B/PPIB protein | Feline |
GM-Tg-cang-T25847-Ab-1/ GM-Tg-cang-T25847-Ab-2 | Canine Cyclophilin B/PPIB protein | Canine |
GM-Tg-bovg-T25847-Ab-1/ GM-Tg-bovg-T25847-Ab-2 | Bovine Cyclophilin B/PPIB protein | Bovine |
GM-Tg-equg-T25847-Ab-1/ GM-Tg-equg-T25847-Ab-2 | Equine Cyclophilin B/PPIB protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
Catalog No. |
GM-Tg-hg-T25847-Ab-1/ GM-Tg-hg-T25847-Ab-2;
GM-Tg-rg-T25847-Ab-1/ GM-Tg-rg-T25847-Ab-2;
GM-Tg-mg-T25847-Ab-1/ GM-Tg-mg-T25847-Ab-2; GM-Tg-cynog-T25847-Ab-1/ GM-Tg-cynog-T25847-Ab-2; GM-Tg-felg-T25847-Ab-1/ GM-Tg-felg-T25847-Ab-2; GM-Tg-cang-T25847-Ab-1/ GM-Tg-cang-T25847-Ab-2; GM-Tg-bovg-T25847-Ab-1/ GM-Tg-bovg-T25847-Ab-2; GM-Tg-equg-T25847-Ab-1/ GM-Tg-equg-T25847-Ab-2 |
Products Name | Cyclophilin B/PPIB protein |
Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
Target Name | Cyclophilin B/PPIB |
Protein Sub-location | Secreted Protein/Potential Cytokines |
Isotypes | Recombinant protein |
Expression platform | Mammalian cell |
Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
Tag | His |
Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine Cyclophilin B/PPIB protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab
GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.