Recombinant multi-species peptide YY/PYY protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine peptide YY/PYY protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the neuropeptide Y (NPY) family of peptides. The encoded preproprotein is proteolytically processed to generate two alternative peptide products that differ in length by three amino acids. These peptides, secreted by endocrine cells in the gut, exhibit different binding affinities for each of the neuropeptide Y receptors. Binding of the encoded peptides to these receptors mediates regulation of pancreatic secretion, gut mobility and energy homeostasis. Rare variations in this gene could increase susceptibility to obesity and elevated serum levels of the encoded peptides may be associated with anorexia nervosa. [provided by RefSeq, Feb 2016]
The Alternative Names of target: peptide YY, PYY,Peptide YY,PYY,PYY-I, Peptide tyrosine tyrosine,PYY1,PYY-I
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Product information
Catalog No. | Product Name | Species Reactivity |
---|---|---|
GM-Tg-hg-T24127-Ab-1/ GM-Tg-hg-T24127-Ab-2 | Human peptide YY/PYY protein | Human |
GM-Tg-rg-T24127-Ab-1/ GM-Tg-rg-T24127-Ab-2 | Rat peptide YY/PYY protein | Rat |
GM-Tg-mg-T24127-Ab-1/ GM-Tg-mg-T24127-Ab-2 | Mouse peptide YY/PYY protein | Mouse |
GM-Tg-cynog-T24127-Ab-1/ GM-Tg-cynog-T24127-Ab-2 | Cynomolgus/Rhesus macaque peptide YY/PYY monoclonal antibody | Cynomolgus/ Rhesus macaque |
GM-Tg-felg-T24127-Ab-1/ GM-Tg-felg-T24127-Ab-2 | Feline peptide YY/PYY protein | Feline |
GM-Tg-cang-T24127-Ab-1/ GM-Tg-cang-T24127-Ab-2 | Canine peptide YY/PYY protein | Canine |
GM-Tg-bovg-T24127-Ab-1/ GM-Tg-bovg-T24127-Ab-2 | Bovine peptide YY/PYY protein | Bovine |
GM-Tg-equg-T24127-Ab-1/ GM-Tg-equg-T24127-Ab-2 | Equine peptide YY/PYY protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
Catalog No. |
GM-Tg-hg-T24127-Ab-1/ GM-Tg-hg-T24127-Ab-2;
GM-Tg-rg-T24127-Ab-1/ GM-Tg-rg-T24127-Ab-2;
GM-Tg-mg-T24127-Ab-1/ GM-Tg-mg-T24127-Ab-2; GM-Tg-cynog-T24127-Ab-1/ GM-Tg-cynog-T24127-Ab-2; GM-Tg-felg-T24127-Ab-1/ GM-Tg-felg-T24127-Ab-2; GM-Tg-cang-T24127-Ab-1/ GM-Tg-cang-T24127-Ab-2; GM-Tg-bovg-T24127-Ab-1/ GM-Tg-bovg-T24127-Ab-2; GM-Tg-equg-T24127-Ab-1/ GM-Tg-equg-T24127-Ab-2 |
Products Name | peptide YY/PYY protein |
Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
Target Name | peptide YY/PYY |
Protein Sub-location | Secreted Protein/Potential Cytokines |
Isotypes | Recombinant protein |
Expression platform | Mammalian cell |
Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
Tag | His |
Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine peptide YY/PYY protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab
GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.