Recombinant multi-species IL-33/IL33 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine IL-33/IL33 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is a cytokine that binds to the IL1RL1/ST2 receptor. The encoded protein is involved in the maturation of Th2 cells and the activation of mast cells, basophils, eosinophils and natural killer cells. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2015]
The Alternative Names of target: 9230117N10Rik,C9orf26,DVS27,IL-33,IL1F11,IL33,Il-33,Il1f11,Il33,Interleukin-1 family member 11 (IL-1F11),Interleukin-33,NF-HEV,NFEHEV,Nuclear factor from high endothelial venules (NF-HEV),RGD1311155

Target products collectionGo to IL-33/IL33 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T23797-Ag-1/ GM-Tg-hg-T23797-Ag-2 Human IL-33/IL33 protein Human
GM-Tg-rg-T23797-Ag-1/ GM-Tg-rg-T23797-Ag-2 Rat IL-33/IL33 protein Rat
GM-Tg-mg-T23797-Ag-1/ GM-Tg-mg-T23797-Ag-2 Mouse IL-33/IL33 protein Mouse
GM-Tg-cynog-T23797-Ag-1/ GM-Tg-cynog-T23797-Ag-2 Cynomolgus/Rhesus macaque IL-33/IL33 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T23797-Ag-1/ GM-Tg-felg-T23797-Ag-2 Feline IL-33/IL33 protein Feline
GM-Tg-cang-T23797-Ag-1/ GM-Tg-cang-T23797-Ag-2 Canine IL-33/IL33 protein Canine
GM-Tg-bovg-T23797-Ag-1/ GM-Tg-bovg-T23797-Ag-2 Bovine IL-33/IL33 protein Bovine
GM-Tg-equg-T23797-Ag-1/ GM-Tg-equg-T23797-Ag-2 Equine IL-33/IL33 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T23797-Ag-1/ GM-Tg-hg-T23797-Ag-2; GM-Tg-rg-T23797-Ag-1/ GM-Tg-rg-T23797-Ag-2;
GM-Tg-mg-T23797-Ag-1/ GM-Tg-mg-T23797-Ag-2; GM-Tg-cynog-T23797-Ag-1/ GM-Tg-cynog-T23797-Ag-2;
GM-Tg-felg-T23797-Ag-1/ GM-Tg-felg-T23797-Ag-2; GM-Tg-cang-T23797-Ag-1/ GM-Tg-cang-T23797-Ag-2;
GM-Tg-bovg-T23797-Ag-1/ GM-Tg-bovg-T23797-Ag-2; GM-Tg-equg-T23797-Ag-1/ GM-Tg-equg-T23797-Ag-2
Products Name IL-33/IL33 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name IL-33/IL33
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine IL-33/IL33 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.