Recombinant multi-species REL protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine REL protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a protein that belongs to the Rel homology domain/immunoglobulin-like fold, plexin, transcription factor (RHD/IPT) family. Members of this family regulate genes involved in apoptosis, inflammation, the immune response, and oncogenic processes. This proto-oncogene plays a role in the survival and proliferation of B lymphocytes. Mutation or amplification of this gene is associated with B-cell lymphomas, including Hodgkin's lymphoma. Single nucleotide polymorphisms in this gene are associated with susceptibility to ulcerative colitis and rheumatoid arthritis. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2014]
The Alternative Names of target: C-Rel,HIVEN86A,IMD92,Proto-oncogene c-Rel,REL,Rel,c-Rel

Target products collectionGo to REL products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T22547-Ag-1/ GM-Tg-hg-T22547-Ag-2 Human REL protein Human
GM-Tg-rg-T22547-Ag-1/ GM-Tg-rg-T22547-Ag-2 Rat REL protein Rat
GM-Tg-mg-T22547-Ag-1/ GM-Tg-mg-T22547-Ag-2 Mouse REL protein Mouse
GM-Tg-cynog-T22547-Ag-1/ GM-Tg-cynog-T22547-Ag-2 Cynomolgus/Rhesus macaque REL protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T22547-Ag-1/ GM-Tg-felg-T22547-Ag-2 Feline REL protein Feline
GM-Tg-cang-T22547-Ag-1/ GM-Tg-cang-T22547-Ag-2 Canine REL protein Canine
GM-Tg-bovg-T22547-Ag-1/ GM-Tg-bovg-T22547-Ag-2 Bovine REL protein Bovine
GM-Tg-equg-T22547-Ag-1/ GM-Tg-equg-T22547-Ag-2 Equine REL protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T22547-Ag-1/ GM-Tg-hg-T22547-Ag-2; GM-Tg-rg-T22547-Ag-1/ GM-Tg-rg-T22547-Ag-2;
GM-Tg-mg-T22547-Ag-1/ GM-Tg-mg-T22547-Ag-2; GM-Tg-cynog-T22547-Ag-1/ GM-Tg-cynog-T22547-Ag-2;
GM-Tg-felg-T22547-Ag-1/ GM-Tg-felg-T22547-Ag-2; GM-Tg-cang-T22547-Ag-1/ GM-Tg-cang-T22547-Ag-2;
GM-Tg-bovg-T22547-Ag-1/ GM-Tg-bovg-T22547-Ag-2; GM-Tg-equg-T22547-Ag-1/ GM-Tg-equg-T22547-Ag-2
Products Name REL protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name REL
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine REL protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.