Recombinant multi-species CCL22/MDC protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CCL22/MDC protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This antimicrobial gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for monocytes, dendritic cells, natural killer cells and for chronically activated T lymphocytes. It also displays a mild activity for primary activated T lymphocytes and has no chemoattractant activity for neutrophils, eosinophils and resting T lymphocytes. The product of this gene binds to chemokine receptor CCR4. This chemokine may play a role in the trafficking of activated T lymphocytes to inflammatory sites and other aspects of activated T lymphocyte physiology. [provided by RefSeq, Sep 2014]
The Alternative Names of target: A-152E5.1,ABCD-1,C-C motif chemokine 22,CC chemokine STCP-1,CCL22,Ccl22,DC/B-CK,DCBCK,MDC,MDC(1-69),Macrophage-derived chemokine,Mdc,SCYA22,STCP-1,Scya22,Small-inducible cytokine A22,Stimulated T-cell chemotactic protein 1
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T22117-Ag-1/ GM-Tg-hg-T22117-Ag-2 | Human CCL22/MDC protein | Human |
| GM-Tg-rg-T22117-Ag-1/ GM-Tg-rg-T22117-Ag-2 | Rat CCL22/MDC protein | Rat |
| GM-Tg-mg-T22117-Ag-1/ GM-Tg-mg-T22117-Ag-2 | Mouse CCL22/MDC protein | Mouse |
| GM-Tg-cynog-T22117-Ag-1/ GM-Tg-cynog-T22117-Ag-2 | Cynomolgus/Rhesus macaque CCL22/MDC protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T22117-Ag-1/ GM-Tg-felg-T22117-Ag-2 | Feline CCL22/MDC protein | Feline |
| GM-Tg-cang-T22117-Ag-1/ GM-Tg-cang-T22117-Ag-2 | Canine CCL22/MDC protein | Canine |
| GM-Tg-bovg-T22117-Ag-1/ GM-Tg-bovg-T22117-Ag-2 | Bovine CCL22/MDC protein | Bovine |
| GM-Tg-equg-T22117-Ag-1/ GM-Tg-equg-T22117-Ag-2 | Equine CCL22/MDC protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-T22117-Ag-1/ GM-Tg-hg-T22117-Ag-2;
GM-Tg-rg-T22117-Ag-1/ GM-Tg-rg-T22117-Ag-2;
GM-Tg-mg-T22117-Ag-1/ GM-Tg-mg-T22117-Ag-2; GM-Tg-cynog-T22117-Ag-1/ GM-Tg-cynog-T22117-Ag-2; GM-Tg-felg-T22117-Ag-1/ GM-Tg-felg-T22117-Ag-2; GM-Tg-cang-T22117-Ag-1/ GM-Tg-cang-T22117-Ag-2; GM-Tg-bovg-T22117-Ag-1/ GM-Tg-bovg-T22117-Ag-2; GM-Tg-equg-T22117-Ag-1/ GM-Tg-equg-T22117-Ag-2 |
| Products Name | CCL22/MDC protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | CCL22/MDC |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CCL22/MDC protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
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entities. Leveraging the sophisticated
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characterized by high binding affinity,
exceptional physicochemical stability, and
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Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
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innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.