Recombinant multi-species CA2/CA-II protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CA2/CA-II protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is one of several isozymes of carbonic anhydrase, which catalyzes reversible hydration of carbon dioxide. Defects in this enzyme are associated with osteopetrosis and renal tubular acidosis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2014]
The Alternative Names of target: CA-II,CA2,CAC,CAII,Ca2,Car-2,Car2,Carbonate dehydratase II,Carbonic anhydrase 2,Carbonic anhydrase C (CAC),Carbonic anhydrase II (CA-II),Cyanamide hydratase CA2,HEL-76,HEL-S-282,Ltw-5,Lvtw-5

Target products collectionGo to CA2/CA-II products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T20401-Ag-1/ GM-Tg-hg-T20401-Ag-2 Human CA2/CA-II protein Human
GM-Tg-rg-T20401-Ag-1/ GM-Tg-rg-T20401-Ag-2 Rat CA2/CA-II protein Rat
GM-Tg-mg-T20401-Ag-1/ GM-Tg-mg-T20401-Ag-2 Mouse CA2/CA-II protein Mouse
GM-Tg-cynog-T20401-Ag-1/ GM-Tg-cynog-T20401-Ag-2 Cynomolgus/Rhesus macaque CA2/CA-II protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T20401-Ag-1/ GM-Tg-felg-T20401-Ag-2 Feline CA2/CA-II protein Feline
GM-Tg-cang-T20401-Ag-1/ GM-Tg-cang-T20401-Ag-2 Canine CA2/CA-II protein Canine
GM-Tg-bovg-T20401-Ag-1/ GM-Tg-bovg-T20401-Ag-2 Bovine CA2/CA-II protein Bovine
GM-Tg-equg-T20401-Ag-1/ GM-Tg-equg-T20401-Ag-2 Equine CA2/CA-II protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T20401-Ag-1/ GM-Tg-hg-T20401-Ag-2; GM-Tg-rg-T20401-Ag-1/ GM-Tg-rg-T20401-Ag-2;
GM-Tg-mg-T20401-Ag-1/ GM-Tg-mg-T20401-Ag-2; GM-Tg-cynog-T20401-Ag-1/ GM-Tg-cynog-T20401-Ag-2;
GM-Tg-felg-T20401-Ag-1/ GM-Tg-felg-T20401-Ag-2; GM-Tg-cang-T20401-Ag-1/ GM-Tg-cang-T20401-Ag-2;
GM-Tg-bovg-T20401-Ag-1/ GM-Tg-bovg-T20401-Ag-2; GM-Tg-equg-T20401-Ag-1/ GM-Tg-equg-T20401-Ag-2
Products Name CA2/CA-II protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name CA2/CA-II
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CA2/CA-II protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.