Recombinant multi-species PARP3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PARP3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene belongs to the PARP family. These enzymes modify nuclear proteins by poly-ADP-ribosylation, which is required for DNA repair, regulation of apoptosis, and maintenance of genomic stability. This gene encodes the poly(ADP-ribosyl)transferase 3, which is preferentially localized to the daughter centriole throughout the cell cycle. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
The Alternative Names of target: PARP3,Protein mono-ADP-ribosyltransferase PARP3,ADP-ribosyltransferase diphtheria toxin-like 3 (ARTD3), DNA ADP-ribosyltransferase PARP3, IRT1, NAD(+) ADP-ribosyltransferase 3 (ADPRT-3), Poly [ADP-ribose] polymerase 3 (PARP-3, hPARP-3), Poly[ADP-ribose] synthase 3 (pADPRT-3),IRT1,ARTD3,ADPRT3,ADPRTL2,ADPRTL3,PADPRT-3

Target products collectionGo to PARP3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T17228-Ab-1/ GM-Tg-hg-T17228-Ab-2 Human PARP3 protein Human
GM-Tg-rg-T17228-Ab-1/ GM-Tg-rg-T17228-Ab-2 Rat PARP3 protein Rat
GM-Tg-mg-T17228-Ab-1/ GM-Tg-mg-T17228-Ab-2 Mouse PARP3 protein Mouse
GM-Tg-cynog-T17228-Ab-1/ GM-Tg-cynog-T17228-Ab-2 Cynomolgus/Rhesus macaque PARP3 monoclonal antibody Cynomolgus/ Rhesus macaque
GM-Tg-felg-T17228-Ab-1/ GM-Tg-felg-T17228-Ab-2 Feline PARP3 protein Feline
GM-Tg-cang-T17228-Ab-1/ GM-Tg-cang-T17228-Ab-2 Canine PARP3 protein Canine
GM-Tg-bovg-T17228-Ab-1/ GM-Tg-bovg-T17228-Ab-2 Bovine PARP3 protein Bovine
GM-Tg-equg-T17228-Ab-1/ GM-Tg-equg-T17228-Ab-2 Equine PARP3 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T17228-Ab-1/ GM-Tg-hg-T17228-Ab-2; GM-Tg-rg-T17228-Ab-1/ GM-Tg-rg-T17228-Ab-2;
GM-Tg-mg-T17228-Ab-1/ GM-Tg-mg-T17228-Ab-2; GM-Tg-cynog-T17228-Ab-1/ GM-Tg-cynog-T17228-Ab-2;
GM-Tg-felg-T17228-Ab-1/ GM-Tg-felg-T17228-Ab-2; GM-Tg-cang-T17228-Ab-1/ GM-Tg-cang-T17228-Ab-2;
GM-Tg-bovg-T17228-Ab-1/ GM-Tg-bovg-T17228-Ab-2; GM-Tg-equg-T17228-Ab-1/ GM-Tg-equg-T17228-Ab-2
Products Name PARP3 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name PARP3
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PARP3 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.