Recombinant multi-species G3BP1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine G3BP1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes one of the DNA-unwinding enzymes which prefers partially unwound 3'-tailed substrates and can also unwind partial RNA/DNA and RNA/RNA duplexes in an ATP-dependent fashion. This enzyme is a member of the heterogeneous nuclear RNA-binding proteins and is also an element of the Ras signal transduction pathway. It binds specifically to the Ras-GTPase-activating protein by associating with its SH3 domain. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008]
The Alternative Names of target: ATP-dependent DNA helicase VIII (hDH VIII),B430204O07,G3BP,G3BP-1,G3BP1,G3bp,G3bp1,GAP SH3 domain-binding protein 1,HDH-VIII,RGD1310666,Ras GTPase-activating protein-binding protein 1,mKIAA4115

Target products collectionGo to G3BP1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T16886-Ag-1/ GM-Tg-hg-T16886-Ag-2 Human G3BP1 protein Human
GM-Tg-rg-T16886-Ag-1/ GM-Tg-rg-T16886-Ag-2 Rat G3BP1 protein Rat
GM-Tg-mg-T16886-Ag-1/ GM-Tg-mg-T16886-Ag-2 Mouse G3BP1 protein Mouse
GM-Tg-cynog-T16886-Ag-1/ GM-Tg-cynog-T16886-Ag-2 Cynomolgus/Rhesus macaque G3BP1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T16886-Ag-1/ GM-Tg-felg-T16886-Ag-2 Feline G3BP1 protein Feline
GM-Tg-cang-T16886-Ag-1/ GM-Tg-cang-T16886-Ag-2 Canine G3BP1 protein Canine
GM-Tg-bovg-T16886-Ag-1/ GM-Tg-bovg-T16886-Ag-2 Bovine G3BP1 protein Bovine
GM-Tg-equg-T16886-Ag-1/ GM-Tg-equg-T16886-Ag-2 Equine G3BP1 protein Equine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T16886-Ag-1/ GM-Tg-hg-T16886-Ag-2; GM-Tg-rg-T16886-Ag-1/ GM-Tg-rg-T16886-Ag-2;
GM-Tg-mg-T16886-Ag-1/ GM-Tg-mg-T16886-Ag-2; GM-Tg-cynog-T16886-Ag-1/ GM-Tg-cynog-T16886-Ag-2;
GM-Tg-felg-T16886-Ag-1/ GM-Tg-felg-T16886-Ag-2; GM-Tg-cang-T16886-Ag-1/ GM-Tg-cang-T16886-Ag-2;
GM-Tg-bovg-T16886-Ag-1/ GM-Tg-bovg-T16886-Ag-2; GM-Tg-equg-T16886-Ag-1/ GM-Tg-equg-T16886-Ag-2
Products Name G3BP1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name G3BP1
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine G3BP1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.