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Recombinant multi-species hCG Alpha/CGA protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine hCG Alpha/CGA protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. The protein encoded by this gene is the alpha subunit and belongs to the glycoprotein hormones alpha chain family. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
The Alternative Names of target: Anterior pituitary glycoprotein hormones common subunit alpha,CG,CG-ALPHA,CG-alpha,CGA,Cga,Choriogonadotropin alpha chain,Chorionic gonadotrophin subunit alpha (CG-alpha),FSH-alpha,FSHA,Follicle-stimulating hormone alpha chain (FSH-alpha),Follitropin alpha chain,GPA1,GPHA1,GPHa,GPHalpha,Glycoprotein hormones alpha chain,Gpa1,HCG,LHA,LSH-alpha,Luteinizing hormone alpha chain (LSH-alpha),Lutropin alpha chain,TSH-alpha,TSHA,Thyroid-stimulating hormone alpha chain (TSH-alpha),Thyrotropin alpha chain,Tsha,aGSU,alpha-GSU,alphaGSU,alphaSU,hCG Alpha
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MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T16650-Ag-1/ GM-Tg-hg-T16650-Ag-2 | Human hCG Alpha/CGA protein | Human |
| GM-Tg-rg-T16650-Ag-1/ GM-Tg-rg-T16650-Ag-2 | Rat hCG Alpha/CGA protein | Rat |
| GM-Tg-mg-T16650-Ag-1/ GM-Tg-mg-T16650-Ag-2 | Mouse hCG Alpha/CGA protein | Mouse |
| GM-Tg-cynog-T16650-Ag-1/ GM-Tg-cynog-T16650-Ag-2 | Cynomolgus/Rhesus macaque hCG Alpha/CGA protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T16650-Ag-1/ GM-Tg-felg-T16650-Ag-2 | Feline hCG Alpha/CGA protein | Feline |
| GM-Tg-cang-T16650-Ag-1/ GM-Tg-cang-T16650-Ag-2 | Canine hCG Alpha/CGA protein | Canine |
| GM-Tg-bovg-T16650-Ag-1/ GM-Tg-bovg-T16650-Ag-2 | Bovine hCG Alpha/CGA protein | Bovine |
| GM-Tg-equg-T16650-Ag-1/ GM-Tg-equg-T16650-Ag-2 | Equine hCG Alpha/CGA protein | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-T16650-Ag-1/ GM-Tg-hg-T16650-Ag-2;
GM-Tg-rg-T16650-Ag-1/ GM-Tg-rg-T16650-Ag-2;
GM-Tg-mg-T16650-Ag-1/ GM-Tg-mg-T16650-Ag-2; GM-Tg-cynog-T16650-Ag-1/ GM-Tg-cynog-T16650-Ag-2; GM-Tg-felg-T16650-Ag-1/ GM-Tg-felg-T16650-Ag-2; GM-Tg-cang-T16650-Ag-1/ GM-Tg-cang-T16650-Ag-2; GM-Tg-bovg-T16650-Ag-1/ GM-Tg-bovg-T16650-Ag-2; GM-Tg-equg-T16650-Ag-1/ GM-Tg-equg-T16650-Ag-2 |
| Products Name | hCG Alpha/CGA protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | hCG Alpha/CGA |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine hCG Alpha/CGA protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab
GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.