Recombinant multi-species GIVA cPLA2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine GIVA cPLA2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the cytosolic phospholipase A2 group IV family. The enzyme catalyzes the hydrolysis of membrane phospholipids to release arachidonic acid which is subsequently metabolized into eicosanoids. Eicosanoids, including prostaglandins and leukotrienes, are lipid-based cellular hormones that regulate hemodynamics, inflammatory responses, and other intracellular pathways. The hydrolysis reaction also produces lysophospholipids that are converted into platelet-activating factor. The enzyme is activated by increased intracellular Ca(2+) levels and phosphorylation, resulting in its translocation from the cytosol and nucleus to perinuclear membrane vesicles. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015]
The Alternative Names of target: Cytosolic phospholipase A2,GIVA cPLA2,GURDP,PLA2,PLA2G1B,PLA2G4,PLA2G4A,Phospholipase A2 group IVA,Pla2c,Pla2g4,Pla2g4a,cPLA2,cPLA2-alpha,cPLA2alpha

Target products collectionGo to GIVA cPLA2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T14834-Ag-1/ GM-Tg-hg-T14834-Ag-2 Human GIVA cPLA2 protein Human
GM-Tg-rg-T14834-Ag-1/ GM-Tg-rg-T14834-Ag-2 Rat GIVA cPLA2 protein Rat
GM-Tg-mg-T14834-Ag-1/ GM-Tg-mg-T14834-Ag-2 Mouse GIVA cPLA2 protein Mouse
GM-Tg-cynog-T14834-Ag-1/ GM-Tg-cynog-T14834-Ag-2 Cynomolgus/Rhesus macaque GIVA cPLA2 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T14834-Ag-1/ GM-Tg-felg-T14834-Ag-2 Feline GIVA cPLA2 protein Feline
GM-Tg-cang-T14834-Ag-1/ GM-Tg-cang-T14834-Ag-2 Canine GIVA cPLA2 protein Canine
GM-Tg-bovg-T14834-Ag-1/ GM-Tg-bovg-T14834-Ag-2 Bovine GIVA cPLA2 protein Bovine
GM-Tg-equg-T14834-Ag-1/ GM-Tg-equg-T14834-Ag-2 Equine GIVA cPLA2 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T14834-Ag-1/ GM-Tg-hg-T14834-Ag-2; GM-Tg-rg-T14834-Ag-1/ GM-Tg-rg-T14834-Ag-2;
GM-Tg-mg-T14834-Ag-1/ GM-Tg-mg-T14834-Ag-2; GM-Tg-cynog-T14834-Ag-1/ GM-Tg-cynog-T14834-Ag-2;
GM-Tg-felg-T14834-Ag-1/ GM-Tg-felg-T14834-Ag-2; GM-Tg-cang-T14834-Ag-1/ GM-Tg-cang-T14834-Ag-2;
GM-Tg-bovg-T14834-Ag-1/ GM-Tg-bovg-T14834-Ag-2; GM-Tg-equg-T14834-Ag-1/ GM-Tg-equg-T14834-Ag-2
Products Name GIVA cPLA2 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name GIVA cPLA2
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine GIVA cPLA2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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