Recombinant multi-species TGF/TGFB2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TGF/TGFB2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGF-beta family members. Disruption of the TGF-beta/SMAD pathway has been implicated in a variety of human cancers. A chromosomal translocation that includes this gene is associated with Peters' anomaly, a congenital defect of the anterior chamber of the eye. Mutations in this gene may be associated with Loeys-Dietz syndrome. This gene encodes multiple isoforms that may undergo similar proteolytic processing. [provided by RefSeq, Aug 2016]
The Alternative Names of target: Cetermin,G-TSF,Glioblastoma-derived T-cell suppressor factor (G-TSF),LDS4,MGF,TGF,TGF-B2,TGF-beta2,TGFB2,TGFbeta2,Tgf-beta2,Tgfb-2,Tgfb2,Transforming growth factor beta-2 proprotein

Target products collectionGo to TGF/TGFB2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T14143-Ag-1/ GM-Tg-hg-T14143-Ag-2 Human TGF/TGFB2 protein Human
GM-Tg-rg-T14143-Ag-1/ GM-Tg-rg-T14143-Ag-2 Rat TGF/TGFB2 protein Rat
GM-Tg-mg-T14143-Ag-1/ GM-Tg-mg-T14143-Ag-2 Mouse TGF/TGFB2 protein Mouse
GM-Tg-cynog-T14143-Ag-1/ GM-Tg-cynog-T14143-Ag-2 Cynomolgus/Rhesus macaque TGF/TGFB2 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T14143-Ag-1/ GM-Tg-felg-T14143-Ag-2 Feline TGF/TGFB2 protein Feline
GM-Tg-cang-T14143-Ag-1/ GM-Tg-cang-T14143-Ag-2 Canine TGF/TGFB2 protein Canine
GM-Tg-bovg-T14143-Ag-1/ GM-Tg-bovg-T14143-Ag-2 Bovine TGF/TGFB2 protein Bovine
GM-Tg-equg-T14143-Ag-1/ GM-Tg-equg-T14143-Ag-2 Equine TGF/TGFB2 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T14143-Ag-1/ GM-Tg-hg-T14143-Ag-2; GM-Tg-rg-T14143-Ag-1/ GM-Tg-rg-T14143-Ag-2;
GM-Tg-mg-T14143-Ag-1/ GM-Tg-mg-T14143-Ag-2; GM-Tg-cynog-T14143-Ag-1/ GM-Tg-cynog-T14143-Ag-2;
GM-Tg-felg-T14143-Ag-1/ GM-Tg-felg-T14143-Ag-2; GM-Tg-cang-T14143-Ag-1/ GM-Tg-cang-T14143-Ag-2;
GM-Tg-bovg-T14143-Ag-1/ GM-Tg-bovg-T14143-Ag-2; GM-Tg-equg-T14143-Ag-1/ GM-Tg-equg-T14143-Ag-2
Products Name TGF/TGFB2 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name TGF/TGFB2
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TGF/TGFB2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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