Recombinant multi-species COP1/RFWD2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine COP1/RFWD2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Enables ubiquitin protein ligase activity. Involved in positive regulation of proteasomal ubiquitin-dependent protein catabolic process; proteasome-mediated ubiquitin-dependent protein catabolic process; and response to ionizing radiation. Part of Cul4A-RING E3 ubiquitin ligase complex. [provided by Alliance of Genome Resources, Apr 2022]
The Alternative Names of target: COP1, RFWD2,E3 ubiquitin-protein ligase COP1,Constitutive photomorphogenesis protein 1 homolog (hCOP1), RING finger and WD repeat domain protein 2, RING finger protein 200, RING-type E3 ubiquitin transferase RFWD2,FAP78,RFWD2,CFAP78,RNF200

Target products collectionGo to COP1/RFWD2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T12819-Ab-1/ GM-Tg-hg-T12819-Ab-2 Human COP1/RFWD2 protein Human
GM-Tg-rg-T12819-Ab-1/ GM-Tg-rg-T12819-Ab-2 Rat COP1/RFWD2 protein Rat
GM-Tg-mg-T12819-Ab-1/ GM-Tg-mg-T12819-Ab-2 Mouse COP1/RFWD2 protein Mouse
GM-Tg-cynog-T12819-Ab-1/ GM-Tg-cynog-T12819-Ab-2 Cynomolgus/Rhesus macaque COP1/RFWD2 monoclonal antibody Cynomolgus/ Rhesus macaque
GM-Tg-felg-T12819-Ab-1/ GM-Tg-felg-T12819-Ab-2 Feline COP1/RFWD2 protein Feline
GM-Tg-cang-T12819-Ab-1/ GM-Tg-cang-T12819-Ab-2 Canine COP1/RFWD2 protein Canine
GM-Tg-bovg-T12819-Ab-1/ GM-Tg-bovg-T12819-Ab-2 Bovine COP1/RFWD2 protein Bovine
GM-Tg-equg-T12819-Ab-1/ GM-Tg-equg-T12819-Ab-2 Equine COP1/RFWD2 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T12819-Ab-1/ GM-Tg-hg-T12819-Ab-2; GM-Tg-rg-T12819-Ab-1/ GM-Tg-rg-T12819-Ab-2;
GM-Tg-mg-T12819-Ab-1/ GM-Tg-mg-T12819-Ab-2; GM-Tg-cynog-T12819-Ab-1/ GM-Tg-cynog-T12819-Ab-2;
GM-Tg-felg-T12819-Ab-1/ GM-Tg-felg-T12819-Ab-2; GM-Tg-cang-T12819-Ab-1/ GM-Tg-cang-T12819-Ab-2;
GM-Tg-bovg-T12819-Ab-1/ GM-Tg-bovg-T12819-Ab-2; GM-Tg-equg-T12819-Ab-1/ GM-Tg-equg-T12819-Ab-2
Products Name COP1/RFWD2 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name COP1/RFWD2
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine COP1/RFWD2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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