Recombinant multi-species Cryptochrome 1/CRY1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine Cryptochrome 1/CRY1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a flavin adenine dinucleotide-binding protein that is a key component of the circadian core oscillator complex, which regulates the circadian clock. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene have been associated with altered sleep patterns. The encoded protein is widely conserved across plants and animals. Loss of the related gene in mouse results in a shortened circadian cycle in complete darkness. [provided by RefSeq, Jan 2014]
The Alternative Names of target: CRY1,Cry1,Cryptochrome 1,Cryptochrome-1,DSPD,PHLL1,Phll1
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T12108-Ag-1/ GM-Tg-hg-T12108-Ag-2 | Human Cryptochrome 1/CRY1 protein | Human |
| GM-Tg-rg-T12108-Ag-1/ GM-Tg-rg-T12108-Ag-2 | Rat Cryptochrome 1/CRY1 protein | Rat |
| GM-Tg-mg-T12108-Ag-1/ GM-Tg-mg-T12108-Ag-2 | Mouse Cryptochrome 1/CRY1 protein | Mouse |
| GM-Tg-cynog-T12108-Ag-1/ GM-Tg-cynog-T12108-Ag-2 | Cynomolgus/Rhesus macaque Cryptochrome 1/CRY1 protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T12108-Ag-1/ GM-Tg-felg-T12108-Ag-2 | Feline Cryptochrome 1/CRY1 protein | Feline |
| GM-Tg-cang-T12108-Ag-1/ GM-Tg-cang-T12108-Ag-2 | Canine Cryptochrome 1/CRY1 protein | Canine |
| GM-Tg-bovg-T12108-Ag-1/ GM-Tg-bovg-T12108-Ag-2 | Bovine Cryptochrome 1/CRY1 protein | Bovine |
| GM-Tg-equg-T12108-Ag-1/ GM-Tg-equg-T12108-Ag-2 | Equine Cryptochrome 1/CRY1 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-T12108-Ag-1/ GM-Tg-hg-T12108-Ag-2;
GM-Tg-rg-T12108-Ag-1/ GM-Tg-rg-T12108-Ag-2;
GM-Tg-mg-T12108-Ag-1/ GM-Tg-mg-T12108-Ag-2; GM-Tg-cynog-T12108-Ag-1/ GM-Tg-cynog-T12108-Ag-2; GM-Tg-felg-T12108-Ag-1/ GM-Tg-felg-T12108-Ag-2; GM-Tg-cang-T12108-Ag-1/ GM-Tg-cang-T12108-Ag-2; GM-Tg-bovg-T12108-Ag-1/ GM-Tg-bovg-T12108-Ag-2; GM-Tg-equg-T12108-Ag-1/ GM-Tg-equg-T12108-Ag-2 |
| Products Name | Cryptochrome 1/CRY1 protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | Cryptochrome 1/CRY1 |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine Cryptochrome 1/CRY1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.