Recombinant multi-species Cryptochrome 1/CRY1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine Cryptochrome 1/CRY1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a flavin adenine dinucleotide-binding protein that is a key component of the circadian core oscillator complex, which regulates the circadian clock. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene have been associated with altered sleep patterns. The encoded protein is widely conserved across plants and animals. Loss of the related gene in mouse results in a shortened circadian cycle in complete darkness. [provided by RefSeq, Jan 2014]
The Alternative Names of target: CRY1,Cry1,Cryptochrome 1,Cryptochrome-1,DSPD,PHLL1,Phll1

Target products collectionGo to Cryptochrome 1/CRY1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T12108-Ag-1/ GM-Tg-hg-T12108-Ag-2 Human Cryptochrome 1/CRY1 protein Human
GM-Tg-rg-T12108-Ag-1/ GM-Tg-rg-T12108-Ag-2 Rat Cryptochrome 1/CRY1 protein Rat
GM-Tg-mg-T12108-Ag-1/ GM-Tg-mg-T12108-Ag-2 Mouse Cryptochrome 1/CRY1 protein Mouse
GM-Tg-cynog-T12108-Ag-1/ GM-Tg-cynog-T12108-Ag-2 Cynomolgus/Rhesus macaque Cryptochrome 1/CRY1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T12108-Ag-1/ GM-Tg-felg-T12108-Ag-2 Feline Cryptochrome 1/CRY1 protein Feline
GM-Tg-cang-T12108-Ag-1/ GM-Tg-cang-T12108-Ag-2 Canine Cryptochrome 1/CRY1 protein Canine
GM-Tg-bovg-T12108-Ag-1/ GM-Tg-bovg-T12108-Ag-2 Bovine Cryptochrome 1/CRY1 protein Bovine
GM-Tg-equg-T12108-Ag-1/ GM-Tg-equg-T12108-Ag-2 Equine Cryptochrome 1/CRY1 protein Equine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T12108-Ag-1/ GM-Tg-hg-T12108-Ag-2; GM-Tg-rg-T12108-Ag-1/ GM-Tg-rg-T12108-Ag-2;
GM-Tg-mg-T12108-Ag-1/ GM-Tg-mg-T12108-Ag-2; GM-Tg-cynog-T12108-Ag-1/ GM-Tg-cynog-T12108-Ag-2;
GM-Tg-felg-T12108-Ag-1/ GM-Tg-felg-T12108-Ag-2; GM-Tg-cang-T12108-Ag-1/ GM-Tg-cang-T12108-Ag-2;
GM-Tg-bovg-T12108-Ag-1/ GM-Tg-bovg-T12108-Ag-2; GM-Tg-equg-T12108-Ag-1/ GM-Tg-equg-T12108-Ag-2
Products Name Cryptochrome 1/CRY1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name Cryptochrome 1/CRY1
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine Cryptochrome 1/CRY1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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