Recombinant multi-species Kallikrein 5/KLK5 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine Kallikrein 5/KLK5 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its expression is up-regulated by estrogens and progestins. The encoded protein is secreted and may be involved in desquamation in the epidermis. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]
The Alternative Names of target: 1110030O19Rik,KLK-L2,KLK5,KLKL2,KLNC,Kallikrein 5,Kallikrein-5,Kallikrein-like protein 2 (KLK-L2),Klk5,SCTE,Stratum corneum tryptic enzyme
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T11808-Ag-1/ GM-Tg-hg-T11808-Ag-2 | Human Kallikrein 5/KLK5 protein | Human |
| GM-Tg-rg-T11808-Ag-1/ GM-Tg-rg-T11808-Ag-2 | Rat Kallikrein 5/KLK5 protein | Rat |
| GM-Tg-mg-T11808-Ag-1/ GM-Tg-mg-T11808-Ag-2 | Mouse Kallikrein 5/KLK5 protein | Mouse |
| GM-Tg-cynog-T11808-Ag-1/ GM-Tg-cynog-T11808-Ag-2 | Cynomolgus/Rhesus macaque Kallikrein 5/KLK5 protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T11808-Ag-1/ GM-Tg-felg-T11808-Ag-2 | Feline Kallikrein 5/KLK5 protein | Feline |
| GM-Tg-cang-T11808-Ag-1/ GM-Tg-cang-T11808-Ag-2 | Canine Kallikrein 5/KLK5 protein | Canine |
| GM-Tg-bovg-T11808-Ag-1/ GM-Tg-bovg-T11808-Ag-2 | Bovine Kallikrein 5/KLK5 protein | Bovine |
| GM-Tg-equg-T11808-Ag-1/ GM-Tg-equg-T11808-Ag-2 | Equine Kallikrein 5/KLK5 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-T11808-Ag-1/ GM-Tg-hg-T11808-Ag-2;
GM-Tg-rg-T11808-Ag-1/ GM-Tg-rg-T11808-Ag-2;
GM-Tg-mg-T11808-Ag-1/ GM-Tg-mg-T11808-Ag-2; GM-Tg-cynog-T11808-Ag-1/ GM-Tg-cynog-T11808-Ag-2; GM-Tg-felg-T11808-Ag-1/ GM-Tg-felg-T11808-Ag-2; GM-Tg-cang-T11808-Ag-1/ GM-Tg-cang-T11808-Ag-2; GM-Tg-bovg-T11808-Ag-1/ GM-Tg-bovg-T11808-Ag-2; GM-Tg-equg-T11808-Ag-1/ GM-Tg-equg-T11808-Ag-2 |
| Products Name | Kallikrein 5/KLK5 protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | Kallikrein 5/KLK5 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine Kallikrein 5/KLK5 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.