Recombinant multi-species CYP2B6 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CYP2B6 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene, CYP2B6, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to metabolize some xenobiotics, such as the anti-cancer drugs cyclophosphamide and ifosphamide. Transcript variants for this gene have been described; however, it has not been resolved whether these transcripts are in fact produced by this gene or by a closely related pseudogene, CYP2B7. Both the gene and the pseudogene are located in the middle of a CYP2A pseudogene found in a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q. [provided by RefSeq, Jul 2008]
The Alternative Names of target: CYP2B6,Cytochrome P450 2B6,1,4-cineole 2-exo-monooxygenase, CYPIIB6, Cytochrome P450 IIB1,CPB6,EFVM,IIB1,P450,CYP2B,CYP2B7,CYP2B7P,CYPIIB6

Target products collectionGo to CYP2B6 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T11793-Ab-1/ GM-Tg-hg-T11793-Ab-2 Human CYP2B6 protein Human
GM-Tg-rg-T11793-Ab-1/ GM-Tg-rg-T11793-Ab-2 Rat CYP2B6 protein Rat
GM-Tg-mg-T11793-Ab-1/ GM-Tg-mg-T11793-Ab-2 Mouse CYP2B6 protein Mouse
GM-Tg-cynog-T11793-Ab-1/ GM-Tg-cynog-T11793-Ab-2 Cynomolgus/Rhesus macaque CYP2B6 monoclonal antibody Cynomolgus/ Rhesus macaque
GM-Tg-felg-T11793-Ab-1/ GM-Tg-felg-T11793-Ab-2 Feline CYP2B6 protein Feline
GM-Tg-cang-T11793-Ab-1/ GM-Tg-cang-T11793-Ab-2 Canine CYP2B6 protein Canine
GM-Tg-bovg-T11793-Ab-1/ GM-Tg-bovg-T11793-Ab-2 Bovine CYP2B6 protein Bovine
GM-Tg-equg-T11793-Ab-1/ GM-Tg-equg-T11793-Ab-2 Equine CYP2B6 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T11793-Ab-1/ GM-Tg-hg-T11793-Ab-2; GM-Tg-rg-T11793-Ab-1/ GM-Tg-rg-T11793-Ab-2;
GM-Tg-mg-T11793-Ab-1/ GM-Tg-mg-T11793-Ab-2; GM-Tg-cynog-T11793-Ab-1/ GM-Tg-cynog-T11793-Ab-2;
GM-Tg-felg-T11793-Ab-1/ GM-Tg-felg-T11793-Ab-2; GM-Tg-cang-T11793-Ab-1/ GM-Tg-cang-T11793-Ab-2;
GM-Tg-bovg-T11793-Ab-1/ GM-Tg-bovg-T11793-Ab-2; GM-Tg-equg-T11793-Ab-1/ GM-Tg-equg-T11793-Ab-2
Products Name CYP2B6 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name CYP2B6
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CYP2B6 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.