Recombinant multi-species IL-31/IL31 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine IL-31/IL31 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
IL31, which is made principally by activated Th2-type T cells, interacts with a heterodimeric receptor consisting of IL31RA (MIM 609510) and OSMR (MIM 601743) that is constitutively expressed on epithelial cells and keratinocytes. IL31 may be involved in the promotion of allergic skin disorders and in regulating other allergic diseases, such as asthma (Dillon et al., 2004 [PubMed 15184896]).[supplied by OMIM, Mar 2008]
The Alternative Names of target: 1700013B14Rik,AABR07036324.1,IL-31,IL31,Il31,Interleukin-31

Target products collectionGo to IL-31/IL31 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T11701-Ag-1/ GM-Tg-hg-T11701-Ag-2 Human IL-31/IL31 protein Human
GM-Tg-rg-T11701-Ag-1/ GM-Tg-rg-T11701-Ag-2 Rat IL-31/IL31 protein Rat
GM-Tg-mg-T11701-Ag-1/ GM-Tg-mg-T11701-Ag-2 Mouse IL-31/IL31 protein Mouse
GM-Tg-cynog-T11701-Ag-1/ GM-Tg-cynog-T11701-Ag-2 Cynomolgus/Rhesus macaque IL-31/IL31 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T11701-Ag-1/ GM-Tg-felg-T11701-Ag-2 Feline IL-31/IL31 protein Feline
GM-Tg-cang-T11701-Ag-1/ GM-Tg-cang-T11701-Ag-2 Canine IL-31/IL31 protein Canine
GM-Tg-bovg-T11701-Ag-1/ GM-Tg-bovg-T11701-Ag-2 Bovine IL-31/IL31 protein Bovine
GM-Tg-equg-T11701-Ag-1/ GM-Tg-equg-T11701-Ag-2 Equine IL-31/IL31 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T11701-Ag-1/ GM-Tg-hg-T11701-Ag-2; GM-Tg-rg-T11701-Ag-1/ GM-Tg-rg-T11701-Ag-2;
GM-Tg-mg-T11701-Ag-1/ GM-Tg-mg-T11701-Ag-2; GM-Tg-cynog-T11701-Ag-1/ GM-Tg-cynog-T11701-Ag-2;
GM-Tg-felg-T11701-Ag-1/ GM-Tg-felg-T11701-Ag-2; GM-Tg-cang-T11701-Ag-1/ GM-Tg-cang-T11701-Ag-2;
GM-Tg-bovg-T11701-Ag-1/ GM-Tg-bovg-T11701-Ag-2; GM-Tg-equg-T11701-Ag-1/ GM-Tg-equg-T11701-Ag-2
Products Name IL-31/IL31 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name IL-31/IL31
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine IL-31/IL31 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.