Recombinant multi-species MYH7 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MYH7 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Muscle myosin is a hexameric protein containing 2 heavy chain subunits, 2 alkali light chain subunits, and 2 regulatory light chain subunits. This gene encodes the beta (or slow) heavy chain subunit of cardiac myosin. It is expressed predominantly in normal human ventricle. It is also expressed in skeletal muscle tissues rich in slow-twitch type I muscle fibers. Changes in the relative abundance of this protein and the alpha (or fast) heavy subunit of cardiac myosin correlate with the contractile velocity of cardiac muscle. Its expression is also altered during thyroid hormone depletion and hemodynamic overloading. Mutations in this gene are associated with familial hypertrophic cardiomyopathy, myosin storage myopathy, dilated cardiomyopathy, and Laing distal myopathy. [provided by RefSeq, May 2022]
The Alternative Names of target: MYH7,Myosin-7,Myosin heavy chain 7, Myosin heavy chain slow isoform (MyHC-slow), Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta),CMH1,MPD1,SPMD,SPMM,CMD1S,MYHCB,CMYO7A,CMYO7B,CMYP7A,CMYP7B

Target products collectionGo to MYH7 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T07507-Ab-1/ GM-Tg-hg-T07507-Ab-2 Human MYH7 protein Human
GM-Tg-rg-T07507-Ab-1/ GM-Tg-rg-T07507-Ab-2 Rat MYH7 protein Rat
GM-Tg-mg-T07507-Ab-1/ GM-Tg-mg-T07507-Ab-2 Mouse MYH7 protein Mouse
GM-Tg-cynog-T07507-Ab-1/ GM-Tg-cynog-T07507-Ab-2 Cynomolgus/Rhesus macaque MYH7 monoclonal antibody Cynomolgus/ Rhesus macaque
GM-Tg-felg-T07507-Ab-1/ GM-Tg-felg-T07507-Ab-2 Feline MYH7 protein Feline
GM-Tg-cang-T07507-Ab-1/ GM-Tg-cang-T07507-Ab-2 Canine MYH7 protein Canine
GM-Tg-bovg-T07507-Ab-1/ GM-Tg-bovg-T07507-Ab-2 Bovine MYH7 protein Bovine
GM-Tg-equg-T07507-Ab-1/ GM-Tg-equg-T07507-Ab-2 Equine MYH7 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T07507-Ab-1/ GM-Tg-hg-T07507-Ab-2; GM-Tg-rg-T07507-Ab-1/ GM-Tg-rg-T07507-Ab-2;
GM-Tg-mg-T07507-Ab-1/ GM-Tg-mg-T07507-Ab-2; GM-Tg-cynog-T07507-Ab-1/ GM-Tg-cynog-T07507-Ab-2;
GM-Tg-felg-T07507-Ab-1/ GM-Tg-felg-T07507-Ab-2; GM-Tg-cang-T07507-Ab-1/ GM-Tg-cang-T07507-Ab-2;
GM-Tg-bovg-T07507-Ab-1/ GM-Tg-bovg-T07507-Ab-2; GM-Tg-equg-T07507-Ab-1/ GM-Tg-equg-T07507-Ab-2
Products Name MYH7 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name MYH7
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MYH7 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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