Recombinant multi-species GHRL protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine GHRL protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes the ghrelin-obestatin preproprotein that is cleaved to yield two peptides, ghrelin and obestatin. Ghrelin is a powerful appetite stimulant and plays an important role in energy homeostasis. Its secretion is initiated when the stomach is empty, whereupon it binds to the growth hormone secretagogue receptor in the hypothalamus which results in the secretion of growth hormone (somatotropin). Ghrelin is thought to regulate multiple activities, including hunger, reward perception via the mesolimbic pathway, gastric acid secretion, gastrointestinal motility, and pancreatic glucose-stimulated insulin secretion. It was initially proposed that obestatin plays an opposing role to ghrelin by promoting satiety and thus decreasing food intake, but this action is still debated. Recent reports suggest multiple metabolic roles for obestatin, including regulating adipocyte function and glucose metabolism. Alternative splicing results in multiple transcript variants. In addition, antisense transcripts for this gene have been identified and may potentially regulate ghrelin-obestatin preproprotein expression. [provided by RefSeq, Nov 2014]
The Alternative Names of target: 2210006E23Rik,Appetite-regulating hormone,GHRL,Gh1-1,Ghr,Ghrl,Growth hormone secretagogue,Growth hormone-releasing peptide,MTLRP,MTLRP-AP,MTLRPAP,Motilin-related peptide,Protein M46,ghrelin,m46

Target products collectionGo to GHRL products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T06850-Ag-1/ GM-Tg-hg-T06850-Ag-2 Human GHRL protein Human
GM-Tg-rg-T06850-Ag-1/ GM-Tg-rg-T06850-Ag-2 Rat GHRL protein Rat
GM-Tg-mg-T06850-Ag-1/ GM-Tg-mg-T06850-Ag-2 Mouse GHRL protein Mouse
GM-Tg-cynog-T06850-Ag-1/ GM-Tg-cynog-T06850-Ag-2 Cynomolgus/Rhesus macaque GHRL protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T06850-Ag-1/ GM-Tg-felg-T06850-Ag-2 Feline GHRL protein Feline
GM-Tg-cang-T06850-Ag-1/ GM-Tg-cang-T06850-Ag-2 Canine GHRL protein Canine
GM-Tg-bovg-T06850-Ag-1/ GM-Tg-bovg-T06850-Ag-2 Bovine GHRL protein Bovine
GM-Tg-equg-T06850-Ag-1/ GM-Tg-equg-T06850-Ag-2 Equine GHRL protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T06850-Ag-1/ GM-Tg-hg-T06850-Ag-2; GM-Tg-rg-T06850-Ag-1/ GM-Tg-rg-T06850-Ag-2;
GM-Tg-mg-T06850-Ag-1/ GM-Tg-mg-T06850-Ag-2; GM-Tg-cynog-T06850-Ag-1/ GM-Tg-cynog-T06850-Ag-2;
GM-Tg-felg-T06850-Ag-1/ GM-Tg-felg-T06850-Ag-2; GM-Tg-cang-T06850-Ag-1/ GM-Tg-cang-T06850-Ag-2;
GM-Tg-bovg-T06850-Ag-1/ GM-Tg-bovg-T06850-Ag-2; GM-Tg-equg-T06850-Ag-1/ GM-Tg-equg-T06850-Ag-2
Products Name GHRL protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name GHRL
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine GHRL protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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