Recombinant multi-species IL-17F/IL17F protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine IL-17F/IL17F protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is a cytokine that shares sequence similarity with IL17. This cytokine is expressed by activated T cells, and has been shown to stimulate the production of several other cytokines, including IL6, IL8, and CSF2/GM_CSF. This cytokine is also found to inhibit the angiogenesis of endothelial cells and induce endothelial cells to produce IL2, TGFB1/TGFB, and monocyte chemoattractant protein-1. [provided by RefSeq, Jul 2008]
The Alternative Names of target: CANDF6,Cytokine ML-1,IL-17F,IL17A,IL17F,Il17f,Interleukin-17F,ML-1,ML1
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Product information
Catalog No. | Product Name | Species Reactivity |
---|---|---|
GM-Tg-hg-T06542-Ag-1/ GM-Tg-hg-T06542-Ag-2 | Human IL-17F/IL17F protein | Human |
GM-Tg-rg-T06542-Ag-1/ GM-Tg-rg-T06542-Ag-2 | Rat IL-17F/IL17F protein | Rat |
GM-Tg-mg-T06542-Ag-1/ GM-Tg-mg-T06542-Ag-2 | Mouse IL-17F/IL17F protein | Mouse |
GM-Tg-cynog-T06542-Ag-1/ GM-Tg-cynog-T06542-Ag-2 | Cynomolgus/Rhesus macaque IL-17F/IL17F protein | Cynomolgus/ Rhesus macaque |
GM-Tg-felg-T06542-Ag-1/ GM-Tg-felg-T06542-Ag-2 | Feline IL-17F/IL17F protein | Feline |
GM-Tg-cang-T06542-Ag-1/ GM-Tg-cang-T06542-Ag-2 | Canine IL-17F/IL17F protein | Canine |
GM-Tg-bovg-T06542-Ag-1/ GM-Tg-bovg-T06542-Ag-2 | Bovine IL-17F/IL17F protein | Bovine |
GM-Tg-equg-T06542-Ag-1/ GM-Tg-equg-T06542-Ag-2 | Equine IL-17F/IL17F protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
Catalog No. |
GM-Tg-hg-T06542-Ag-1/ GM-Tg-hg-T06542-Ag-2;
GM-Tg-rg-T06542-Ag-1/ GM-Tg-rg-T06542-Ag-2;
GM-Tg-mg-T06542-Ag-1/ GM-Tg-mg-T06542-Ag-2; GM-Tg-cynog-T06542-Ag-1/ GM-Tg-cynog-T06542-Ag-2; GM-Tg-felg-T06542-Ag-1/ GM-Tg-felg-T06542-Ag-2; GM-Tg-cang-T06542-Ag-1/ GM-Tg-cang-T06542-Ag-2; GM-Tg-bovg-T06542-Ag-1/ GM-Tg-bovg-T06542-Ag-2; GM-Tg-equg-T06542-Ag-1/ GM-Tg-equg-T06542-Ag-2 |
Products Name | IL-17F/IL17F protein |
Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
Target Name | IL-17F/IL17F |
Protein Sub-location | Secreted Protein/Potential Cytokines |
Isotypes | Recombinant protein |
Expression platform | Mammalian cell |
Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
Tag | His |
Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine IL-17F/IL17F protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab
GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.