Recombinant multi-species CCL20/MIP-3 alpha protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CCL20/MIP-3 alpha protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This antimicrobial gene belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The protein encoded by this gene displays chemotactic activity for lymphocytes and can repress proliferation of myeloid progenitors. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2014]
The Alternative Names of target: Beta-chemokine exodus-1,C-C motif chemokine 20,CC chemokine LARC,CCL20,CKb4,Ccl20,Exodus,LARC,Liver and activation-regulated chemokine,MIP-3 alpha,MIP-3-alpha,MIP-3A,MIP-3[a],MIP-3a,MIP3A,Macrophage inflammatory protein 3 alpha (MIP-3-alpha),SCYA20,ST38,Scya20,Small-inducible cytokine A20,exodus-1

Target products collectionGo to CCL20/MIP-3 alpha products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T04894-Ag-1/ GM-Tg-hg-T04894-Ag-2 Human CCL20/MIP-3 alpha protein Human
GM-Tg-rg-T04894-Ag-1/ GM-Tg-rg-T04894-Ag-2 Rat CCL20/MIP-3 alpha protein Rat
GM-Tg-mg-T04894-Ag-1/ GM-Tg-mg-T04894-Ag-2 Mouse CCL20/MIP-3 alpha protein Mouse
GM-Tg-cynog-T04894-Ag-1/ GM-Tg-cynog-T04894-Ag-2 Cynomolgus/Rhesus macaque CCL20/MIP-3 alpha protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T04894-Ag-1/ GM-Tg-felg-T04894-Ag-2 Feline CCL20/MIP-3 alpha protein Feline
GM-Tg-cang-T04894-Ag-1/ GM-Tg-cang-T04894-Ag-2 Canine CCL20/MIP-3 alpha protein Canine
GM-Tg-bovg-T04894-Ag-1/ GM-Tg-bovg-T04894-Ag-2 Bovine CCL20/MIP-3 alpha protein Bovine
GM-Tg-equg-T04894-Ag-1/ GM-Tg-equg-T04894-Ag-2 Equine CCL20/MIP-3 alpha protein Equine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T04894-Ag-1/ GM-Tg-hg-T04894-Ag-2; GM-Tg-rg-T04894-Ag-1/ GM-Tg-rg-T04894-Ag-2;
GM-Tg-mg-T04894-Ag-1/ GM-Tg-mg-T04894-Ag-2; GM-Tg-cynog-T04894-Ag-1/ GM-Tg-cynog-T04894-Ag-2;
GM-Tg-felg-T04894-Ag-1/ GM-Tg-felg-T04894-Ag-2; GM-Tg-cang-T04894-Ag-1/ GM-Tg-cang-T04894-Ag-2;
GM-Tg-bovg-T04894-Ag-1/ GM-Tg-bovg-T04894-Ag-2; GM-Tg-equg-T04894-Ag-1/ GM-Tg-equg-T04894-Ag-2
Products Name CCL20/MIP-3 alpha protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name CCL20/MIP-3 alpha
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CCL20/MIP-3 alpha protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

    GDU
    GDU

    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.