Recombinant multi-species CUL3/CUL-3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CUL3/CUL-3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the cullin protein family. The encoded protein plays a critical role in the polyubiquitination and subsequent degradation of specific protein substrates as the core component and scaffold protein of an E3 ubiquitin ligase complex. Complexes including the encoded protein may also play a role in late endosome maturation. Mutations in this gene are a cause of type 2E pseudohypoaldosteronism. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Mar 2012]
The Alternative Names of target: CUL-3,CUL3,Cul3,Cullin-3,KIAA0617,NEDAUS,PHA2E,cullin-3

Target products collectionGo to CUL3/CUL-3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T04364-Ag-1/ GM-Tg-hg-T04364-Ag-2 Human CUL3/CUL-3 protein Human
GM-Tg-rg-T04364-Ag-1/ GM-Tg-rg-T04364-Ag-2 Rat CUL3/CUL-3 protein Rat
GM-Tg-mg-T04364-Ag-1/ GM-Tg-mg-T04364-Ag-2 Mouse CUL3/CUL-3 protein Mouse
GM-Tg-cynog-T04364-Ag-1/ GM-Tg-cynog-T04364-Ag-2 Cynomolgus/Rhesus macaque CUL3/CUL-3 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T04364-Ag-1/ GM-Tg-felg-T04364-Ag-2 Feline CUL3/CUL-3 protein Feline
GM-Tg-cang-T04364-Ag-1/ GM-Tg-cang-T04364-Ag-2 Canine CUL3/CUL-3 protein Canine
GM-Tg-bovg-T04364-Ag-1/ GM-Tg-bovg-T04364-Ag-2 Bovine CUL3/CUL-3 protein Bovine
GM-Tg-equg-T04364-Ag-1/ GM-Tg-equg-T04364-Ag-2 Equine CUL3/CUL-3 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T04364-Ag-1/ GM-Tg-hg-T04364-Ag-2; GM-Tg-rg-T04364-Ag-1/ GM-Tg-rg-T04364-Ag-2;
GM-Tg-mg-T04364-Ag-1/ GM-Tg-mg-T04364-Ag-2; GM-Tg-cynog-T04364-Ag-1/ GM-Tg-cynog-T04364-Ag-2;
GM-Tg-felg-T04364-Ag-1/ GM-Tg-felg-T04364-Ag-2; GM-Tg-cang-T04364-Ag-1/ GM-Tg-cang-T04364-Ag-2;
GM-Tg-bovg-T04364-Ag-1/ GM-Tg-bovg-T04364-Ag-2; GM-Tg-equg-T04364-Ag-1/ GM-Tg-equg-T04364-Ag-2
Products Name CUL3/CUL-3 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name CUL3/CUL-3
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CUL3/CUL-3 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

    GDU
    GDU

    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.