Recombinant multi-species Midkine/MDK protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine Midkine/MDK protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of a small family of secreted growth factors that binds heparin and responds to retinoic acid. The encoded protein promotes cell growth, migration, and angiogenesis, in particular during tumorigenesis. This gene has been targeted as a therapeutic for a variety of different disorders. Alternatively spliced transcript variants encoding multiple isoforms have been observed. [provided by RefSeq, Jul 2012]
The Alternative Names of target: Midkine, MDK,Midkine,MK,Amphiregulin-associated protein (ARAP), Midgestation and kidney protein, Neurite outgrowth-promoting factor 2, Neurite outgrowth-promoting protein,MK,ARAP,NEGF2

Target products collectionGo to Midkine/MDK products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T03878-Ab-1/ GM-Tg-hg-T03878-Ab-2 Human Midkine/MDK protein Human
GM-Tg-rg-T03878-Ab-1/ GM-Tg-rg-T03878-Ab-2 Rat Midkine/MDK protein Rat
GM-Tg-mg-T03878-Ab-1/ GM-Tg-mg-T03878-Ab-2 Mouse Midkine/MDK protein Mouse
GM-Tg-cynog-T03878-Ab-1/ GM-Tg-cynog-T03878-Ab-2 Cynomolgus/Rhesus macaque Midkine/MDK monoclonal antibody Cynomolgus/ Rhesus macaque
GM-Tg-felg-T03878-Ab-1/ GM-Tg-felg-T03878-Ab-2 Feline Midkine/MDK protein Feline
GM-Tg-cang-T03878-Ab-1/ GM-Tg-cang-T03878-Ab-2 Canine Midkine/MDK protein Canine
GM-Tg-bovg-T03878-Ab-1/ GM-Tg-bovg-T03878-Ab-2 Bovine Midkine/MDK protein Bovine
GM-Tg-equg-T03878-Ab-1/ GM-Tg-equg-T03878-Ab-2 Equine Midkine/MDK protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T03878-Ab-1/ GM-Tg-hg-T03878-Ab-2; GM-Tg-rg-T03878-Ab-1/ GM-Tg-rg-T03878-Ab-2;
GM-Tg-mg-T03878-Ab-1/ GM-Tg-mg-T03878-Ab-2; GM-Tg-cynog-T03878-Ab-1/ GM-Tg-cynog-T03878-Ab-2;
GM-Tg-felg-T03878-Ab-1/ GM-Tg-felg-T03878-Ab-2; GM-Tg-cang-T03878-Ab-1/ GM-Tg-cang-T03878-Ab-2;
GM-Tg-bovg-T03878-Ab-1/ GM-Tg-bovg-T03878-Ab-2; GM-Tg-equg-T03878-Ab-1/ GM-Tg-equg-T03878-Ab-2
Products Name Midkine/MDK protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name Midkine/MDK
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine Midkine/MDK protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.