Recombinant multi-species HDAC9 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine HDAC9 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to the Xenopus and mouse MITR genes. The MITR protein lacks the histone deacetylase catalytic domain. It represses MEF2 activity through recruitment of multicomponent corepressor complexes that include CtBP and HDACs. This encoded protein may play a role in hematopoiesis. Multiple alternatively spliced transcripts have been described for this gene but the full-length nature of some of them has not been determined. [provided by RefSeq, Jul 2008]
The Alternative Names of target: ARCND4,D030072B18Rik,HD7,HD7B,HD7b,HD7b),HD9,HDAC,HDAC7,HDAC7B,HDAC9,HDAC9B,HDAC9FL,HDRP,Hdac7b,Hdac9,Histone deacetylase 7B (HD7,Histone deacetylase 9,Histone deacetylase-related protein,MEF2-interacting transcription repressor MITR,MITR,Mitr,RGD1310748,RGD1563092,TWIST,mKIAA0744

Target products collectionGo to HDAC9 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T03687-Ag-1/ GM-Tg-hg-T03687-Ag-2 Human HDAC9 protein Human
GM-Tg-rg-T03687-Ag-1/ GM-Tg-rg-T03687-Ag-2 Rat HDAC9 protein Rat
GM-Tg-mg-T03687-Ag-1/ GM-Tg-mg-T03687-Ag-2 Mouse HDAC9 protein Mouse
GM-Tg-cynog-T03687-Ag-1/ GM-Tg-cynog-T03687-Ag-2 Cynomolgus/Rhesus macaque HDAC9 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T03687-Ag-1/ GM-Tg-felg-T03687-Ag-2 Feline HDAC9 protein Feline
GM-Tg-cang-T03687-Ag-1/ GM-Tg-cang-T03687-Ag-2 Canine HDAC9 protein Canine
GM-Tg-bovg-T03687-Ag-1/ GM-Tg-bovg-T03687-Ag-2 Bovine HDAC9 protein Bovine
GM-Tg-equg-T03687-Ag-1/ GM-Tg-equg-T03687-Ag-2 Equine HDAC9 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T03687-Ag-1/ GM-Tg-hg-T03687-Ag-2; GM-Tg-rg-T03687-Ag-1/ GM-Tg-rg-T03687-Ag-2;
GM-Tg-mg-T03687-Ag-1/ GM-Tg-mg-T03687-Ag-2; GM-Tg-cynog-T03687-Ag-1/ GM-Tg-cynog-T03687-Ag-2;
GM-Tg-felg-T03687-Ag-1/ GM-Tg-felg-T03687-Ag-2; GM-Tg-cang-T03687-Ag-1/ GM-Tg-cang-T03687-Ag-2;
GM-Tg-bovg-T03687-Ag-1/ GM-Tg-bovg-T03687-Ag-2; GM-Tg-equg-T03687-Ag-1/ GM-Tg-equg-T03687-Ag-2
Products Name HDAC9 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name HDAC9
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine HDAC9 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.