Recombinant multi-species SOX2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine SOX2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT). [provided by RefSeq, Jul 2008]
The Alternative Names of target: ANOP3,MCOPS3,RGD1565646,SOX2,Sox-2,Sox2,Transcription factor SOX-2,lcc,ysb

Target products collectionGo to SOX2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T00724-Ag-1/ GM-Tg-hg-T00724-Ag-2 Human SOX2 protein Human
GM-Tg-rg-T00724-Ag-1/ GM-Tg-rg-T00724-Ag-2 Rat SOX2 protein Rat
GM-Tg-mg-T00724-Ag-1/ GM-Tg-mg-T00724-Ag-2 Mouse SOX2 protein Mouse
GM-Tg-cynog-T00724-Ag-1/ GM-Tg-cynog-T00724-Ag-2 Cynomolgus/Rhesus macaque SOX2 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T00724-Ag-1/ GM-Tg-felg-T00724-Ag-2 Feline SOX2 protein Feline
GM-Tg-cang-T00724-Ag-1/ GM-Tg-cang-T00724-Ag-2 Canine SOX2 protein Canine
GM-Tg-bovg-T00724-Ag-1/ GM-Tg-bovg-T00724-Ag-2 Bovine SOX2 protein Bovine
GM-Tg-equg-T00724-Ag-1/ GM-Tg-equg-T00724-Ag-2 Equine SOX2 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T00724-Ag-1/ GM-Tg-hg-T00724-Ag-2; GM-Tg-rg-T00724-Ag-1/ GM-Tg-rg-T00724-Ag-2;
GM-Tg-mg-T00724-Ag-1/ GM-Tg-mg-T00724-Ag-2; GM-Tg-cynog-T00724-Ag-1/ GM-Tg-cynog-T00724-Ag-2;
GM-Tg-felg-T00724-Ag-1/ GM-Tg-felg-T00724-Ag-2; GM-Tg-cang-T00724-Ag-1/ GM-Tg-cang-T00724-Ag-2;
GM-Tg-bovg-T00724-Ag-1/ GM-Tg-bovg-T00724-Ag-2; GM-Tg-equg-T00724-Ag-1/ GM-Tg-equg-T00724-Ag-2
Products Name SOX2 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name SOX2
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine SOX2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

    GDU
    GDU

    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.