Recombinant multi-species OPN/Osteopontin/SPP1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine OPN/Osteopontin/SPP1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is involved in the attachment of osteoclasts to the mineralized bone matrix. The encoded protein is secreted and binds hydroxyapatite with high affinity. The osteoclast vitronectin receptor is found in the cell membrane and may be involved in the binding to this protein. This protein is also a cytokine that upregulates expression of interferon-gamma and interleukin-12. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
The Alternative Names of target: OPN, Osteopontin, SPP1,Osteopontin,Bone sialoprotein 1, Nephropontin, Secreted phosphoprotein 1 (SPP-1), Urinary stone protein, Uropontin,OPN,BNSP,BSPI,ETA-1
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Product information
Catalog No. | Product Name | Species Reactivity |
---|---|---|
GM-Tg-hg-T00032-Ab-1/ GM-Tg-hg-T00032-Ab-2 | Human OPN/Osteopontin/SPP1 protein | Human |
GM-Tg-rg-T00032-Ab-1/ GM-Tg-rg-T00032-Ab-2 | Rat OPN/Osteopontin/SPP1 protein | Rat |
GM-Tg-mg-T00032-Ab-1/ GM-Tg-mg-T00032-Ab-2 | Mouse OPN/Osteopontin/SPP1 protein | Mouse |
GM-Tg-cynog-T00032-Ab-1/ GM-Tg-cynog-T00032-Ab-2 | Cynomolgus/Rhesus macaque OPN/Osteopontin/SPP1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
GM-Tg-felg-T00032-Ab-1/ GM-Tg-felg-T00032-Ab-2 | Feline OPN/Osteopontin/SPP1 protein | Feline |
GM-Tg-cang-T00032-Ab-1/ GM-Tg-cang-T00032-Ab-2 | Canine OPN/Osteopontin/SPP1 protein | Canine |
GM-Tg-bovg-T00032-Ab-1/ GM-Tg-bovg-T00032-Ab-2 | Bovine OPN/Osteopontin/SPP1 protein | Bovine |
GM-Tg-equg-T00032-Ab-1/ GM-Tg-equg-T00032-Ab-2 | Equine OPN/Osteopontin/SPP1 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
Catalog No. |
GM-Tg-hg-T00032-Ab-1/ GM-Tg-hg-T00032-Ab-2;
GM-Tg-rg-T00032-Ab-1/ GM-Tg-rg-T00032-Ab-2;
GM-Tg-mg-T00032-Ab-1/ GM-Tg-mg-T00032-Ab-2; GM-Tg-cynog-T00032-Ab-1/ GM-Tg-cynog-T00032-Ab-2; GM-Tg-felg-T00032-Ab-1/ GM-Tg-felg-T00032-Ab-2; GM-Tg-cang-T00032-Ab-1/ GM-Tg-cang-T00032-Ab-2; GM-Tg-bovg-T00032-Ab-1/ GM-Tg-bovg-T00032-Ab-2; GM-Tg-equg-T00032-Ab-1/ GM-Tg-equg-T00032-Ab-2 |
Products Name | OPN/Osteopontin/SPP1 protein |
Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
Target Name | OPN/Osteopontin/SPP1 |
Protein Sub-location | Secreted Protein/Potential Cytokines |
Isotypes | Recombinant protein |
Expression platform | Mammalian cell |
Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
Tag | His |
Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine OPN/Osteopontin/SPP1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab
GMab, developed by GeneMedi, constitutes an
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