Recombinant multi-species BAG6 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine BAG6 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene was first characterized as part of a cluster of genes located within the human major histocompatibility complex class III region. This gene encodes a nuclear protein that is cleaved by caspase 3 and is implicated in the control of apoptosis. In addition, the protein forms a complex with E1A binding protein p300 and is required for the acetylation of p53 in response to DNA damage. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
The Alternative Names of target: 2410045D21Rik,BAG family molecular chaperone regulator 6,BAG-6,BAG6,BAT3,BCL2-associated athanogene 6 (BAG-6),Bag6,Bat3,D17H6S52E,D6S52E,G3,HLA-B-associated transcript 3,Large proline-rich protein BAG6,Protein G3,Protein Scythe,Scythe

Target products collectionGo to BAG6 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-SE1653-Ag-1/ GM-Tg-hg-SE1653-Ag-2 Human BAG6 protein Human
GM-Tg-rg-SE1653-Ag-1/ GM-Tg-rg-SE1653-Ag-2 Rat BAG6 protein Rat
GM-Tg-mg-SE1653-Ag-1/ GM-Tg-mg-SE1653-Ag-2 Mouse BAG6 protein Mouse
GM-Tg-cynog-SE1653-Ag-1/ GM-Tg-cynog-SE1653-Ag-2 Cynomolgus/Rhesus macaque BAG6 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-SE1653-Ag-1/ GM-Tg-felg-SE1653-Ag-2 Feline BAG6 protein Feline
GM-Tg-cang-SE1653-Ag-1/ GM-Tg-cang-SE1653-Ag-2 Canine BAG6 protein Canine
GM-Tg-bovg-SE1653-Ag-1/ GM-Tg-bovg-SE1653-Ag-2 Bovine BAG6 protein Bovine
GM-Tg-equg-SE1653-Ag-1/ GM-Tg-equg-SE1653-Ag-2 Equine BAG6 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-SE1653-Ag-1/ GM-Tg-hg-SE1653-Ag-2; GM-Tg-rg-SE1653-Ag-1/ GM-Tg-rg-SE1653-Ag-2;
GM-Tg-mg-SE1653-Ag-1/ GM-Tg-mg-SE1653-Ag-2; GM-Tg-cynog-SE1653-Ag-1/ GM-Tg-cynog-SE1653-Ag-2;
GM-Tg-felg-SE1653-Ag-1/ GM-Tg-felg-SE1653-Ag-2; GM-Tg-cang-SE1653-Ag-1/ GM-Tg-cang-SE1653-Ag-2;
GM-Tg-bovg-SE1653-Ag-1/ GM-Tg-bovg-SE1653-Ag-2; GM-Tg-equg-SE1653-Ag-1/ GM-Tg-equg-SE1653-Ag-2
Products Name BAG6 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name BAG6
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine BAG6 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.