Recombinant multi-species ERp57/ERp60/PDIA3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ERp57/ERp60/PDIA3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a protein of the endoplasmic reticulum that interacts with lectin chaperones calreticulin and calnexin to modulate folding of newly synthesized glycoproteins. The protein was once thought to be a phospholipase; however, it has been demonstrated that the protein actually has protein disulfide isomerase activity. It is thought that complexes of lectins and this protein mediate protein folding by promoting formation of disulfide bonds in their glycoprotein substrates. This protein also functions as a molecular chaperone that prevents the formation of protein aggregates. [provided by RefSeq, Dec 2016]
The Alternative Names of target: 58 kDa glucose-regulated protein,58 kDa microsomal protein (p58),58kDa,Disulfide isomerase ER-60,ER60,ERp57,ERp57),ERp60,ERp60),ERp61,Endoplasmic reticulum resident protein 57 (ER protein 57,Endoplasmic reticulum resident protein 60 (ER protein 60,Erp,GRP57,GRP58,Grp58,HEL-S-269,HEL-S-93n,HsT17083,P58,PDI,PDI-Q2,PDIA3,PI-PLC,PLC[a],Pdia3,Plca,Protein disulfide-isomerase A3

Target products collectionGo to ERp57/ERp60/PDIA3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-SE1578-Ag-1/ GM-Tg-hg-SE1578-Ag-2 Human ERp57/ERp60/PDIA3 protein Human
GM-Tg-rg-SE1578-Ag-1/ GM-Tg-rg-SE1578-Ag-2 Rat ERp57/ERp60/PDIA3 protein Rat
GM-Tg-mg-SE1578-Ag-1/ GM-Tg-mg-SE1578-Ag-2 Mouse ERp57/ERp60/PDIA3 protein Mouse
GM-Tg-cynog-SE1578-Ag-1/ GM-Tg-cynog-SE1578-Ag-2 Cynomolgus/Rhesus macaque ERp57/ERp60/PDIA3 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-SE1578-Ag-1/ GM-Tg-felg-SE1578-Ag-2 Feline ERp57/ERp60/PDIA3 protein Feline
GM-Tg-cang-SE1578-Ag-1/ GM-Tg-cang-SE1578-Ag-2 Canine ERp57/ERp60/PDIA3 protein Canine
GM-Tg-bovg-SE1578-Ag-1/ GM-Tg-bovg-SE1578-Ag-2 Bovine ERp57/ERp60/PDIA3 protein Bovine
GM-Tg-equg-SE1578-Ag-1/ GM-Tg-equg-SE1578-Ag-2 Equine ERp57/ERp60/PDIA3 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-SE1578-Ag-1/ GM-Tg-hg-SE1578-Ag-2; GM-Tg-rg-SE1578-Ag-1/ GM-Tg-rg-SE1578-Ag-2;
GM-Tg-mg-SE1578-Ag-1/ GM-Tg-mg-SE1578-Ag-2; GM-Tg-cynog-SE1578-Ag-1/ GM-Tg-cynog-SE1578-Ag-2;
GM-Tg-felg-SE1578-Ag-1/ GM-Tg-felg-SE1578-Ag-2; GM-Tg-cang-SE1578-Ag-1/ GM-Tg-cang-SE1578-Ag-2;
GM-Tg-bovg-SE1578-Ag-1/ GM-Tg-bovg-SE1578-Ag-2; GM-Tg-equg-SE1578-Ag-1/ GM-Tg-equg-SE1578-Ag-2
Products Name ERp57/ERp60/PDIA3 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name ERp57/ERp60/PDIA3
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ERp57/ERp60/PDIA3 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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