Recombinant multi-species CLPX protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CLPX protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is part of a protease found in mitochondria. This protease is ATP-dependent and targets specific proteins for degradation. The protease consists of two heptameric rings of the CLPP catalytic subunit sandwiched between two hexameric rings of the chaperone subunit encoded by this gene. Targeted proteins are unwound by this protein and then passed on to the CLPP subunit for degradation. Two transcript variants, one protein-coding and the other non-protein coding, have been found for this gene. [provided by RefSeq, Nov 2015]
The Alternative Names of target: ATP-dependent Clp protease ATP-binding subunit clpX-like,ATP-dependent clpX-like chaperone,CLPX,Caseinolytic mitochondrial matrix peptidase chaperone subunit X,Clpx,E330029I21,EPP2,mitochondrial

Target products collectionGo to CLPX products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-SE1576-Ag-1/ GM-Tg-hg-SE1576-Ag-2 Human CLPX protein Human
GM-Tg-rg-SE1576-Ag-1/ GM-Tg-rg-SE1576-Ag-2 Rat CLPX protein Rat
GM-Tg-mg-SE1576-Ag-1/ GM-Tg-mg-SE1576-Ag-2 Mouse CLPX protein Mouse
GM-Tg-cynog-SE1576-Ag-1/ GM-Tg-cynog-SE1576-Ag-2 Cynomolgus/Rhesus macaque CLPX protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-SE1576-Ag-1/ GM-Tg-felg-SE1576-Ag-2 Feline CLPX protein Feline
GM-Tg-cang-SE1576-Ag-1/ GM-Tg-cang-SE1576-Ag-2 Canine CLPX protein Canine
GM-Tg-bovg-SE1576-Ag-1/ GM-Tg-bovg-SE1576-Ag-2 Bovine CLPX protein Bovine
GM-Tg-equg-SE1576-Ag-1/ GM-Tg-equg-SE1576-Ag-2 Equine CLPX protein Equine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-SE1576-Ag-1/ GM-Tg-hg-SE1576-Ag-2; GM-Tg-rg-SE1576-Ag-1/ GM-Tg-rg-SE1576-Ag-2;
GM-Tg-mg-SE1576-Ag-1/ GM-Tg-mg-SE1576-Ag-2; GM-Tg-cynog-SE1576-Ag-1/ GM-Tg-cynog-SE1576-Ag-2;
GM-Tg-felg-SE1576-Ag-1/ GM-Tg-felg-SE1576-Ag-2; GM-Tg-cang-SE1576-Ag-1/ GM-Tg-cang-SE1576-Ag-2;
GM-Tg-bovg-SE1576-Ag-1/ GM-Tg-bovg-SE1576-Ag-2; GM-Tg-equg-SE1576-Ag-1/ GM-Tg-equg-SE1576-Ag-2
Products Name CLPX protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name CLPX
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CLPX protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

    GDU
    GDU

    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.