Recombinant multi-species CLPX protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CLPX protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is part of a protease found in mitochondria. This protease is ATP-dependent and targets specific proteins for degradation. The protease consists of two heptameric rings of the CLPP catalytic subunit sandwiched between two hexameric rings of the chaperone subunit encoded by this gene. Targeted proteins are unwound by this protein and then passed on to the CLPP subunit for degradation. Two transcript variants, one protein-coding and the other non-protein coding, have been found for this gene. [provided by RefSeq, Nov 2015]
The Alternative Names of target: ATP-dependent Clp protease ATP-binding subunit clpX-like,ATP-dependent clpX-like chaperone,CLPX,Caseinolytic mitochondrial matrix peptidase chaperone subunit X,Clpx,E330029I21,EPP2,mitochondrial
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE1576-Ag-1/ GM-Tg-hg-SE1576-Ag-2 | Human CLPX protein | Human |
| GM-Tg-rg-SE1576-Ag-1/ GM-Tg-rg-SE1576-Ag-2 | Rat CLPX protein | Rat |
| GM-Tg-mg-SE1576-Ag-1/ GM-Tg-mg-SE1576-Ag-2 | Mouse CLPX protein | Mouse |
| GM-Tg-cynog-SE1576-Ag-1/ GM-Tg-cynog-SE1576-Ag-2 | Cynomolgus/Rhesus macaque CLPX protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE1576-Ag-1/ GM-Tg-felg-SE1576-Ag-2 | Feline CLPX protein | Feline |
| GM-Tg-cang-SE1576-Ag-1/ GM-Tg-cang-SE1576-Ag-2 | Canine CLPX protein | Canine |
| GM-Tg-bovg-SE1576-Ag-1/ GM-Tg-bovg-SE1576-Ag-2 | Bovine CLPX protein | Bovine |
| GM-Tg-equg-SE1576-Ag-1/ GM-Tg-equg-SE1576-Ag-2 | Equine CLPX protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-SE1576-Ag-1/ GM-Tg-hg-SE1576-Ag-2;
GM-Tg-rg-SE1576-Ag-1/ GM-Tg-rg-SE1576-Ag-2;
GM-Tg-mg-SE1576-Ag-1/ GM-Tg-mg-SE1576-Ag-2; GM-Tg-cynog-SE1576-Ag-1/ GM-Tg-cynog-SE1576-Ag-2; GM-Tg-felg-SE1576-Ag-1/ GM-Tg-felg-SE1576-Ag-2; GM-Tg-cang-SE1576-Ag-1/ GM-Tg-cang-SE1576-Ag-2; GM-Tg-bovg-SE1576-Ag-1/ GM-Tg-bovg-SE1576-Ag-2; GM-Tg-equg-SE1576-Ag-1/ GM-Tg-equg-SE1576-Ag-2 |
| Products Name | CLPX protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | CLPX |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CLPX protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
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characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.