Recombinant multi-species CEP57 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CEP57 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a cytoplasmic protein called Translokin. This protein localizes to the centrosome and has a function in microtubular stabilization. The N-terminal half of this protein is required for its centrosome localization and for its multimerization, and the C-terminal half is required for nucleating, bundling and anchoring microtubules to the centrosomes. This protein specifically interacts with fibroblast growth factor 2 (FGF2), sorting nexin 6, Ran-binding protein M and the kinesins KIF3A and KIF3B, and thus mediates the nuclear translocation and mitogenic activity of the FGF2. It also interacts with cyclin D1 and controls nucleocytoplasmic distribution of the cyclin D1 in quiescent cells. This protein is crucial for maintaining correct chromosomal number during cell division. Mutations in this gene cause mosaic variegated aneuploidy syndrome, a rare autosomal recessive disorder. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011]
The Alternative Names of target: 3110002L15Rik,3110002l15rik,4921510P06Rik,4931428M20Rik,CEP57,Centrosomal protein of 57 kDa,Cep57,FGF2-interacting protein,MVA2,PIG8,RGD1309884,TSP57,Testis-specific protein 57,Translokin,Tsp57,mKIAA0092

Target products collectionGo to CEP57 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-SE1572-Ag-1/ GM-Tg-hg-SE1572-Ag-2 Human CEP57 protein Human
GM-Tg-rg-SE1572-Ag-1/ GM-Tg-rg-SE1572-Ag-2 Rat CEP57 protein Rat
GM-Tg-mg-SE1572-Ag-1/ GM-Tg-mg-SE1572-Ag-2 Mouse CEP57 protein Mouse
GM-Tg-cynog-SE1572-Ag-1/ GM-Tg-cynog-SE1572-Ag-2 Cynomolgus/Rhesus macaque CEP57 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-SE1572-Ag-1/ GM-Tg-felg-SE1572-Ag-2 Feline CEP57 protein Feline
GM-Tg-cang-SE1572-Ag-1/ GM-Tg-cang-SE1572-Ag-2 Canine CEP57 protein Canine
GM-Tg-bovg-SE1572-Ag-1/ GM-Tg-bovg-SE1572-Ag-2 Bovine CEP57 protein Bovine
GM-Tg-equg-SE1572-Ag-1/ GM-Tg-equg-SE1572-Ag-2 Equine CEP57 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-SE1572-Ag-1/ GM-Tg-hg-SE1572-Ag-2; GM-Tg-rg-SE1572-Ag-1/ GM-Tg-rg-SE1572-Ag-2;
GM-Tg-mg-SE1572-Ag-1/ GM-Tg-mg-SE1572-Ag-2; GM-Tg-cynog-SE1572-Ag-1/ GM-Tg-cynog-SE1572-Ag-2;
GM-Tg-felg-SE1572-Ag-1/ GM-Tg-felg-SE1572-Ag-2; GM-Tg-cang-SE1572-Ag-1/ GM-Tg-cang-SE1572-Ag-2;
GM-Tg-bovg-SE1572-Ag-1/ GM-Tg-bovg-SE1572-Ag-2; GM-Tg-equg-SE1572-Ag-1/ GM-Tg-equg-SE1572-Ag-2
Products Name CEP57 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name CEP57
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CEP57 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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