Recombinant multi-species AK3L1/AK4 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine AK3L1/AK4 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the adenylate kinase family of enzymes. The encoded protein is localized to the mitochondrial matrix. Adenylate kinases regulate the adenine and guanine nucleotide compositions within a cell by catalyzing the reversible transfer of phosphate group among these nucleotides. Five isozymes of adenylate kinase have been identified in vertebrates. Expression of these isozymes is tissue-specific and developmentally regulated. A pseudogene for this gene has been located on chromosome 17. Three transcript variants encoding the same protein have been identified for this gene. Sequence alignment suggests that the gene defined by NM_013410, NM_203464, and NM_001005353 is located on chromosome 1. [provided by RefSeq, Jul 2008]
The Alternative Names of target: AK 4,AK3,AK3L1,AK3L2,AK4,Adenylate kinase 3-like,Adenylate kinase 4,Ak-3,Ak-4,Ak3,Ak3l1,Ak3l2,Ak4,D4Ertd274e,GTP:AMP phosphotransferase AK4,mitochondrial

Target products collectionGo to AK3L1/AK4 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-SE1556-Ag-1/ GM-Tg-hg-SE1556-Ag-2 Human AK3L1/AK4 protein Human
GM-Tg-rg-SE1556-Ag-1/ GM-Tg-rg-SE1556-Ag-2 Rat AK3L1/AK4 protein Rat
GM-Tg-mg-SE1556-Ag-1/ GM-Tg-mg-SE1556-Ag-2 Mouse AK3L1/AK4 protein Mouse
GM-Tg-cynog-SE1556-Ag-1/ GM-Tg-cynog-SE1556-Ag-2 Cynomolgus/Rhesus macaque AK3L1/AK4 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-SE1556-Ag-1/ GM-Tg-felg-SE1556-Ag-2 Feline AK3L1/AK4 protein Feline
GM-Tg-cang-SE1556-Ag-1/ GM-Tg-cang-SE1556-Ag-2 Canine AK3L1/AK4 protein Canine
GM-Tg-bovg-SE1556-Ag-1/ GM-Tg-bovg-SE1556-Ag-2 Bovine AK3L1/AK4 protein Bovine
GM-Tg-equg-SE1556-Ag-1/ GM-Tg-equg-SE1556-Ag-2 Equine AK3L1/AK4 protein Equine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-SE1556-Ag-1/ GM-Tg-hg-SE1556-Ag-2; GM-Tg-rg-SE1556-Ag-1/ GM-Tg-rg-SE1556-Ag-2;
GM-Tg-mg-SE1556-Ag-1/ GM-Tg-mg-SE1556-Ag-2; GM-Tg-cynog-SE1556-Ag-1/ GM-Tg-cynog-SE1556-Ag-2;
GM-Tg-felg-SE1556-Ag-1/ GM-Tg-felg-SE1556-Ag-2; GM-Tg-cang-SE1556-Ag-1/ GM-Tg-cang-SE1556-Ag-2;
GM-Tg-bovg-SE1556-Ag-1/ GM-Tg-bovg-SE1556-Ag-2; GM-Tg-equg-SE1556-Ag-1/ GM-Tg-equg-SE1556-Ag-2
Products Name AK3L1/AK4 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name AK3L1/AK4
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine AK3L1/AK4 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.