Recombinant multi-species AK3L1/AK4 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine AK3L1/AK4 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the adenylate kinase family of enzymes. The encoded protein is localized to the mitochondrial matrix. Adenylate kinases regulate the adenine and guanine nucleotide compositions within a cell by catalyzing the reversible transfer of phosphate group among these nucleotides. Five isozymes of adenylate kinase have been identified in vertebrates. Expression of these isozymes is tissue-specific and developmentally regulated. A pseudogene for this gene has been located on chromosome 17. Three transcript variants encoding the same protein have been identified for this gene. Sequence alignment suggests that the gene defined by NM_013410, NM_203464, and NM_001005353 is located on chromosome 1. [provided by RefSeq, Jul 2008]
The Alternative Names of target: AK 4,AK3,AK3L1,AK3L2,AK4,Adenylate kinase 3-like,Adenylate kinase 4,Ak-3,Ak-4,Ak3,Ak3l1,Ak3l2,Ak4,D4Ertd274e,GTP:AMP phosphotransferase AK4,mitochondrial
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE1556-Ag-1/ GM-Tg-hg-SE1556-Ag-2 | Human AK3L1/AK4 protein | Human |
| GM-Tg-rg-SE1556-Ag-1/ GM-Tg-rg-SE1556-Ag-2 | Rat AK3L1/AK4 protein | Rat |
| GM-Tg-mg-SE1556-Ag-1/ GM-Tg-mg-SE1556-Ag-2 | Mouse AK3L1/AK4 protein | Mouse |
| GM-Tg-cynog-SE1556-Ag-1/ GM-Tg-cynog-SE1556-Ag-2 | Cynomolgus/Rhesus macaque AK3L1/AK4 protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE1556-Ag-1/ GM-Tg-felg-SE1556-Ag-2 | Feline AK3L1/AK4 protein | Feline |
| GM-Tg-cang-SE1556-Ag-1/ GM-Tg-cang-SE1556-Ag-2 | Canine AK3L1/AK4 protein | Canine |
| GM-Tg-bovg-SE1556-Ag-1/ GM-Tg-bovg-SE1556-Ag-2 | Bovine AK3L1/AK4 protein | Bovine |
| GM-Tg-equg-SE1556-Ag-1/ GM-Tg-equg-SE1556-Ag-2 | Equine AK3L1/AK4 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-SE1556-Ag-1/ GM-Tg-hg-SE1556-Ag-2;
GM-Tg-rg-SE1556-Ag-1/ GM-Tg-rg-SE1556-Ag-2;
GM-Tg-mg-SE1556-Ag-1/ GM-Tg-mg-SE1556-Ag-2; GM-Tg-cynog-SE1556-Ag-1/ GM-Tg-cynog-SE1556-Ag-2; GM-Tg-felg-SE1556-Ag-1/ GM-Tg-felg-SE1556-Ag-2; GM-Tg-cang-SE1556-Ag-1/ GM-Tg-cang-SE1556-Ag-2; GM-Tg-bovg-SE1556-Ag-1/ GM-Tg-bovg-SE1556-Ag-2; GM-Tg-equg-SE1556-Ag-1/ GM-Tg-equg-SE1556-Ag-2 |
| Products Name | AK3L1/AK4 protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | AK3L1/AK4 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine AK3L1/AK4 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.