Recombinant multi-species ALAS2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ALAS2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The product of this gene specifies an erythroid-specific mitochondrially located enzyme. The encoded protein catalyzes the first step in the heme biosynthetic pathway. Defects in this gene cause X-linked pyridoxine-responsive sideroblastic anemia. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
The Alternative Names of target: ALAS2,5-aminolevulinate synthase, erythroid-specific, mitochondrial,ALAS-E,5-aminolevulinic acid synthase 2, Delta-ALA synthase 2, Delta-aminolevulinate synthase 2,ASB,ANH1,XLSA,ALASE,XLDPP,XLEPP,ALAS-E,SIDBA1

Target products collectionGo to ALAS2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-SE1547-Ab-1/ GM-Tg-hg-SE1547-Ab-2 Human ALAS2 protein Human
GM-Tg-rg-SE1547-Ab-1/ GM-Tg-rg-SE1547-Ab-2 Rat ALAS2 protein Rat
GM-Tg-mg-SE1547-Ab-1/ GM-Tg-mg-SE1547-Ab-2 Mouse ALAS2 protein Mouse
GM-Tg-cynog-SE1547-Ab-1/ GM-Tg-cynog-SE1547-Ab-2 Cynomolgus/Rhesus macaque ALAS2 monoclonal antibody Cynomolgus/ Rhesus macaque
GM-Tg-felg-SE1547-Ab-1/ GM-Tg-felg-SE1547-Ab-2 Feline ALAS2 protein Feline
GM-Tg-cang-SE1547-Ab-1/ GM-Tg-cang-SE1547-Ab-2 Canine ALAS2 protein Canine
GM-Tg-bovg-SE1547-Ab-1/ GM-Tg-bovg-SE1547-Ab-2 Bovine ALAS2 protein Bovine
GM-Tg-equg-SE1547-Ab-1/ GM-Tg-equg-SE1547-Ab-2 Equine ALAS2 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-SE1547-Ab-1/ GM-Tg-hg-SE1547-Ab-2; GM-Tg-rg-SE1547-Ab-1/ GM-Tg-rg-SE1547-Ab-2;
GM-Tg-mg-SE1547-Ab-1/ GM-Tg-mg-SE1547-Ab-2; GM-Tg-cynog-SE1547-Ab-1/ GM-Tg-cynog-SE1547-Ab-2;
GM-Tg-felg-SE1547-Ab-1/ GM-Tg-felg-SE1547-Ab-2; GM-Tg-cang-SE1547-Ab-1/ GM-Tg-cang-SE1547-Ab-2;
GM-Tg-bovg-SE1547-Ab-1/ GM-Tg-bovg-SE1547-Ab-2; GM-Tg-equg-SE1547-Ab-1/ GM-Tg-equg-SE1547-Ab-2
Products Name ALAS2 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name ALAS2
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ALAS2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.