Recombinant multi-species MRPL24 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MRPL24 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein which is more than twice the size of its E.coli counterpart (EcoL24). Sequence analysis identified two transcript variants that encode the same protein. [provided by RefSeq, Jul 2008]
The Alternative Names of target: 2010005E08Rik,2810470K06Rik,39S ribosomal protein L24,6720473G22Rik,L24mt,Large ribosomal subunit protein uL24m,MRP-L18,MRP-L24,MRP-L24),MRPL24,Mrpl24,mitochondrial (L24mt,mrpl24,uL24m
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Product information
Catalog No. | Product Name | Species Reactivity |
---|---|---|
GM-Tg-hg-SE1522-Ag-1/ GM-Tg-hg-SE1522-Ag-2 | Human MRPL24 protein | Human |
GM-Tg-rg-SE1522-Ag-1/ GM-Tg-rg-SE1522-Ag-2 | Rat MRPL24 protein | Rat |
GM-Tg-mg-SE1522-Ag-1/ GM-Tg-mg-SE1522-Ag-2 | Mouse MRPL24 protein | Mouse |
GM-Tg-cynog-SE1522-Ag-1/ GM-Tg-cynog-SE1522-Ag-2 | Cynomolgus/Rhesus macaque MRPL24 protein | Cynomolgus/ Rhesus macaque |
GM-Tg-felg-SE1522-Ag-1/ GM-Tg-felg-SE1522-Ag-2 | Feline MRPL24 protein | Feline |
GM-Tg-cang-SE1522-Ag-1/ GM-Tg-cang-SE1522-Ag-2 | Canine MRPL24 protein | Canine |
GM-Tg-bovg-SE1522-Ag-1/ GM-Tg-bovg-SE1522-Ag-2 | Bovine MRPL24 protein | Bovine |
GM-Tg-equg-SE1522-Ag-1/ GM-Tg-equg-SE1522-Ag-2 | Equine MRPL24 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
Catalog No. |
GM-Tg-hg-SE1522-Ag-1/ GM-Tg-hg-SE1522-Ag-2;
GM-Tg-rg-SE1522-Ag-1/ GM-Tg-rg-SE1522-Ag-2;
GM-Tg-mg-SE1522-Ag-1/ GM-Tg-mg-SE1522-Ag-2; GM-Tg-cynog-SE1522-Ag-1/ GM-Tg-cynog-SE1522-Ag-2; GM-Tg-felg-SE1522-Ag-1/ GM-Tg-felg-SE1522-Ag-2; GM-Tg-cang-SE1522-Ag-1/ GM-Tg-cang-SE1522-Ag-2; GM-Tg-bovg-SE1522-Ag-1/ GM-Tg-bovg-SE1522-Ag-2; GM-Tg-equg-SE1522-Ag-1/ GM-Tg-equg-SE1522-Ag-2 |
Products Name | MRPL24 protein |
Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
Target Name | MRPL24 |
Protein Sub-location | Secreted Protein/Potential Cytokines |
Isotypes | Recombinant protein |
Expression platform | Mammalian cell |
Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
Tag | His |
Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MRPL24 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab
GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.