Recombinant multi-species ASCL1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ASCL1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the basic helix-loop-helix (BHLH) family of transcription factors. The protein activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. This protein plays a role in the neuronal commitment and differentiation and in the generation of olfactory and autonomic neurons. Mutations in this gene may contribute to the congenital central hypoventilation syndrome (CCHS) phenotype in rare cases. [provided by RefSeq, Jul 2008]
The Alternative Names of target: ASCL1,ASH-1,ASH1,Achaete-scute homolog 1,Ascl1,Class A basic helix-loop-helix protein 46 (bHLHa46),HASH1,MASH1,Mash1,bHLHa46,hASH1

Target products collectionGo to ASCL1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-SE1510-Ag-1/ GM-Tg-hg-SE1510-Ag-2 Human ASCL1 protein Human
GM-Tg-rg-SE1510-Ag-1/ GM-Tg-rg-SE1510-Ag-2 Rat ASCL1 protein Rat
GM-Tg-mg-SE1510-Ag-1/ GM-Tg-mg-SE1510-Ag-2 Mouse ASCL1 protein Mouse
GM-Tg-cynog-SE1510-Ag-1/ GM-Tg-cynog-SE1510-Ag-2 Cynomolgus/Rhesus macaque ASCL1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-SE1510-Ag-1/ GM-Tg-felg-SE1510-Ag-2 Feline ASCL1 protein Feline
GM-Tg-cang-SE1510-Ag-1/ GM-Tg-cang-SE1510-Ag-2 Canine ASCL1 protein Canine
GM-Tg-bovg-SE1510-Ag-1/ GM-Tg-bovg-SE1510-Ag-2 Bovine ASCL1 protein Bovine
GM-Tg-equg-SE1510-Ag-1/ GM-Tg-equg-SE1510-Ag-2 Equine ASCL1 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-SE1510-Ag-1/ GM-Tg-hg-SE1510-Ag-2; GM-Tg-rg-SE1510-Ag-1/ GM-Tg-rg-SE1510-Ag-2;
GM-Tg-mg-SE1510-Ag-1/ GM-Tg-mg-SE1510-Ag-2; GM-Tg-cynog-SE1510-Ag-1/ GM-Tg-cynog-SE1510-Ag-2;
GM-Tg-felg-SE1510-Ag-1/ GM-Tg-felg-SE1510-Ag-2; GM-Tg-cang-SE1510-Ag-1/ GM-Tg-cang-SE1510-Ag-2;
GM-Tg-bovg-SE1510-Ag-1/ GM-Tg-bovg-SE1510-Ag-2; GM-Tg-equg-SE1510-Ag-1/ GM-Tg-equg-SE1510-Ag-2
Products Name ASCL1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name ASCL1
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ASCL1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.