Recombinant multi-species RDH5 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine RDH5 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes an enzyme belonging to the short-chain dehydrogenases/reductases (SDR) family. This retinol dehydrogenase functions to catalyze the final step in the biosynthesis of 11-cis retinaldehyde, which is the universal chromophore of visual pigments. Mutations in this gene cause autosomal recessive fundus albipunctatus, a rare form of night blindness that is characterized by a delay in the regeneration of cone and rod photopigments. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring upstream BLOC1S1 (biogenesis of lysosomal organelles complex-1, subunit 1) gene. [provided by RefSeq, Dec 2010]
The Alternative Names of target: 11-cis RoDH),11-cis retinol dehydrogenase (11-cis RDH,9-cis,9-cis retinol dehydrogenase (9cRDH),9cRDH,HSD17B9,P32,RDH1,RDH4,RDH5,Rdh1,Rdh5,Retinol dehydrogenase 5,SDR9C5,Short chain dehydrogenase/reductase family 9C member 5,cRDH

Target products collectionGo to RDH5 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-SE1504-Ag-1/ GM-Tg-hg-SE1504-Ag-2 Human RDH5 protein Human
GM-Tg-rg-SE1504-Ag-1/ GM-Tg-rg-SE1504-Ag-2 Rat RDH5 protein Rat
GM-Tg-mg-SE1504-Ag-1/ GM-Tg-mg-SE1504-Ag-2 Mouse RDH5 protein Mouse
GM-Tg-cynog-SE1504-Ag-1/ GM-Tg-cynog-SE1504-Ag-2 Cynomolgus/Rhesus macaque RDH5 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-SE1504-Ag-1/ GM-Tg-felg-SE1504-Ag-2 Feline RDH5 protein Feline
GM-Tg-cang-SE1504-Ag-1/ GM-Tg-cang-SE1504-Ag-2 Canine RDH5 protein Canine
GM-Tg-bovg-SE1504-Ag-1/ GM-Tg-bovg-SE1504-Ag-2 Bovine RDH5 protein Bovine
GM-Tg-equg-SE1504-Ag-1/ GM-Tg-equg-SE1504-Ag-2 Equine RDH5 protein Equine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-SE1504-Ag-1/ GM-Tg-hg-SE1504-Ag-2; GM-Tg-rg-SE1504-Ag-1/ GM-Tg-rg-SE1504-Ag-2;
GM-Tg-mg-SE1504-Ag-1/ GM-Tg-mg-SE1504-Ag-2; GM-Tg-cynog-SE1504-Ag-1/ GM-Tg-cynog-SE1504-Ag-2;
GM-Tg-felg-SE1504-Ag-1/ GM-Tg-felg-SE1504-Ag-2; GM-Tg-cang-SE1504-Ag-1/ GM-Tg-cang-SE1504-Ag-2;
GM-Tg-bovg-SE1504-Ag-1/ GM-Tg-bovg-SE1504-Ag-2; GM-Tg-equg-SE1504-Ag-1/ GM-Tg-equg-SE1504-Ag-2
Products Name RDH5 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name RDH5
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine RDH5 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.